Association of XRCC3 Thr241Met Polymorphisms and Gliomas Risk: Evidence from a Meta-analysis

Association Between the XRCC3 Thr241Met Polymorphism and Cervical Cancer Risk: a Meta-analysis

“…In addition, our results were consistent with the conclusions of many previous studies, which showed no associations between the XRCC3 Thr241Met polymorphism and cancer risk in all of studies, but association was found in Asians, such as Lung cancer, colorectal cancer and glioma (Liang et al, 2013;Tian et al, 2013;Wang et al, 2013). These analyses confirmed the liability of the results.…”

DNA repair gene XRCC3 variants are associated with susceptibility to glioma in a Chinese population

“…Previous studies found that the XRCC3 Thr241Met (rs861539) polymorphism may influence DNA repair capacity and also showed that the XRCC3 Thr241Met polymorphism may be associated with cancer risk (Matullo et al, 2006;Liu et al, 2007;López-Cima et al, 2007;Romanowicz-Makowska et al, 2012). Numerous studies have examined the relationship between the XRCC3 Thr241Met polymorphism and glioma risk, and meta-analysis studies showed positive results (Liang et al, 2013;Zhao et al, 2013;Wang et al, 2014) and also some negative results (Kiuru et al, 2008;Feng et al, 2014). The association strength between XRCC3 Thr241Met and glioma susceptibility remains unclear and requires further analysis.…”

The RTEL1 rs6010620 Polymorphism and Glioma Risk: a Meta-analysis Based on 12 Case-control Studies

“…Up to date previous published articles found that many gene variations may associate with glioma risk, such as XRCC1 mutations, XRCC3 mutations, IDH mutations etc. The gene polymorphisms increased or decreased glioma sensibility by regulating the proliferation and apoptosis of cells (Das et al, 2013;Liang et al, 2013). (Das et al, 2013;Li et al, 2013b) (Shete et al, 2009;Wrensch et al, 2009;Jin et al, 2013;Li et al, 2013;Walcott et al, 2013;Walsh et al, 2013a;Walsh et al, 2013b).…”