Associations Between Depression/Anxiety and Headache Frequency in Migraineurs: A Cross‐Sectional Study

Chu, Hsuan‐Te; Liang, Chih‐Sung; Lee, Jiunn‐Tay; Yeh, Ta‐Chuan; Lee, Meei-Shyuan; Sung, Yueh‐Feng; Yang, Fu‐Chi

doi:10.1111/head.13215

Cited by 59 publications

(54 citation statements)

References 41 publications

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“…In this study, we also observed that the presence of family history, smoking, higher anxiety score, and poor sleep quality were significantly associated with higher risks of migraine. The relationship between anxiety, sleep quality, and migraine has been previously assessed and published [41,42]. Moreover, in our present study, differences in family history associated with both sex and migraine were observed.…”

Section: Fig 2 Age At Onset In Patients With and Without A Family Hisupporting

confidence: 68%

Associations between migraine occurrence and the effect of aura, age at onset, family history, and sex: A cross-sectional study

et al. 2020

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IntroductionThe relationships between family history, sex, age at onset, and migraine occurrence have been documented. However, the associations between these factors across different sexes and subgroups of patients have yet to be elucidated. This study evaluated the association between family history and migraine in male and female patients experiencing episodic and chronic migraine with and without aura. MethodsThis cross-sectional, case-control study included 299 headache-free controls and 885 patients receiving outpatient treatment for migraine. Participants were classified into episodic (1-14 days/month) and chronic (�15 days/month) migraine groups. ResultsPositive family history was significantly more frequently observed in the episodic group than in the chronic group (49.5% vs. 26%; P < 0.001) in male patients, particularly in male patients without aura (50.3% vs. 21.9%; P = 0.003); it was less frequently observed (58.7% vs. 73.7%; P = 0.048) in female patients with aura. Family history was correlated with an earlier age at onset (20.7 years vs. 22.8 years; P = 0.002), particularly in patients without aura (21 years vs. 23.7 years; P = 0.002), who were women (20.9 years vs. 23.9 years; P = 0.002).

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Section: Fig 2 Age At Onset In Patients With and Without A Family Hisupporting

confidence: 68%

Associations between migraine occurrence and the effect of aura, age at onset, family history, and sex: A cross-sectional study

et al. 2020

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“…However since those studies do not specify crossing the 15 day per month headache day threshold among people with migraine or report the diagnoses of CM or CDH they were not included in this manuscript based upon the pre‐identified scope and search terms . And an expanding body of literature demonstrates that increasing headache day frequency across the spectrum is associated with greater disease burden , …”

Section: Discussionmentioning

confidence: 99%

Migraine Progression: A Systematic Review

et al. 2018

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Background Migraine is a common and often debilitating neurological disease. It can be divided into episodic and chronic subforms based on the number of monthly headache days. Because only a subset of individuals with episodic migraine (EM) progress to chronic migraine (CM) over any given time period, understanding the factors that predict the new onset of CM or “migraine progression” may provide insights into the mechanisms, pathophysiology, prevention, and treatment of CM. In this review, we identify and summarize studies that report risk factors associated with the new onset of CM or related chronic headache diagnoses, group these risk factors and report the strength of evidence for the identified risk factors. Objective To conduct a systematic review of studies that identify risk factors for the new onset of CM or related chronic headache diagnoses such as transformed migraine (TM) and chronic daily headache (CDH). Methods Herein we summarize the findings of studies of risk factors associated with the new onset of CM/TM, CDH, or related diagnoses from the English language literature published before March 2018. The PubMed database was searched for relevant studies. Longitudinal studies with follow‐up data and case‐control studies were included in this qualitative synthesis. We report methodology, analytic criteria, and results for each manuscript and for the parent study. Next, we review the strength of evidence for each of the identified risk factors using a modified version of AB Hill’s criteria for causation and rank evidence as fair, moderate, or strong. We categorized risk factors as nonmodifiable, modifiable and based on putative mechanisms. We further categorized risk factors into sociodemographics, lifestyle factors and habits, headache features, comorbid and concomitant diseases and conditions and pharmacologic treatment‐related. Finally, we review theories of the pathophysiology underlying the development of new onset chronic migraine or increasing attack frequency. Results The PubMed search yielded 1870 records after duplicates were removed. Nine additional records were identified through expert consultation and other methods (eg, citations found as references in manuscripts identified in the literature review and through communication with the authors of manuscripts included in the review). The 1879 manuscripts were screened against the inclusion and exclusion criteria and 109 were found to be potentially eligible. Of 109 full‐text articles, 17 studies were identified as meeting the prespecified criteria based on the consensus of all authors. Of the 17 full texts, 13 were longitudinal cohort studies and 4 were case‐controlled studies. We found strength of evidence ranging from fair to strong for the identified risk factors. The strongest data were found for increased headache day frequency, depression, and medication overuse/high‐frequency use. Risk factors for new onset CM and CDH in children and adolescents were similar to those identified in adults. Conclusions A range of risk factors for the n...

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“…72 Interestingly, pharmacological treatment for insomnia did not replicate the behavioral treatment studies. 80 The sleep-headache-mood symptom constellation is a common and sometimes challenging case. The treatment group did exhibit a decrease in nighttime awakenings but all headache endpoints were equal to placebo, including [76][77][78] Insomnia and/or daytime sleepiness are symptoms of mood and anxiety disorders as well as chemical dependencies.…”

Section: Assess Sleep Disturbance and Insomnia In Chronicmentioning

confidence: 99%

“…79 Migraine frequency correlates with greater levels of depression and anxiety. 80 The sleep-headache-mood symptom constellation is a common and sometimes challenging case. In some cases, depression will respond to treatment for sleep and migraine.…”

Section: Assess Sleep Disturbance and Insomnia In Chronicmentioning

confidence: 99%

Sleep and Migraine: Assessment and Treatment of Comorbid Sleep Disorders

Rains

2018

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The relationship of sleep and migraine is unequivocal and familiarity with the nature and magnitude of these associations may inform clinical practice. Recent prospective, longitudinal, and time-series analysis has begun to unravel the magnitude and temporal patterns of sleep and migraine. Prospective evidence has shown that sleep variables can trigger acute migraine, precede and predict new onset headache by several years, and indeed, sleep disturbance and snoring are risk factors for chronification. The presence of a sleep disorder is associated with more frequent and severe migraine and portends a poorer headache prognosis. Interestingly, the disorders linked to migraine are quite varied, including insomnia, snoring and obstructive sleep apnea, restless legs, circadian rhythm disorders, narcolepsy, and others. Insomnia is by far the most common sleep disorder in headache patients. In fact, the majority of patients with chronic migraine presenting for treatment have insomnia. Despite a rapidly expanding literature, very few controlled treatment studies have been published to guide clinical practice. This paper focuses on clinical assessment and treatment of sleep disorders. An algorithm is presented for sleep disorders management in the migraine patient, which highlights major sleep disorders and psychiatric comorbidity. Diagnostic procedures are recommended that are conducive to clinical practice. Suggested tools include the sleep history, screening mnemonics, prediction equation, and sleep diary. New developments in treatment have produced abbreviated and cost-effective therapies for insomnia and obstructive sleep apnea that may reach a larger population. Revisions in the diagnostic manuals for sleep and headache disorders enhance recognition of sleep-related headache. Recommendations include behavioral sleep regulation, shown in recent controlled trials to decrease migraine frequency, management for sleep apnea headache, cognitive behavioral therapy (CBT) for insomnia abbreviated for the physician practice setting, sleep-related headache trigger, and others. There is no empirical evidence that sleep evaluation should delay or supersede usual headache care. Rather, sleep management is complimentary to standard headache practice.

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Associations Between Depression/Anxiety and Headache Frequency in Migraineurs: A Cross‐Sectional Study

Abstract: Higher migraine frequency, either with or without auras, correlated with higher symptom scores of anxiety and depression.

Cited by 59 publications

References 41 publications

Associations between migraine occurrence and the effect of aura, age at onset, family history, and sex: A cross-sectional study

Associations between migraine occurrence and the effect of aura, age at onset, family history, and sex: A cross-sectional study

Migraine Progression: A Systematic Review

Sleep and Migraine: Assessment and Treatment of Comorbid Sleep Disorders

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