Associations between nicotine dependence, anhedonia, urgency and smoking motives

Roys, Melanie R.; Weed, Keri; Carrigan, Maureen H.; MacKillop, James

doi:10.1016/j.addbeh.2016.06.002

Cited by 65 publications

(15 citation statements)

References 37 publications

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“…To counter the adverse effects of cigarette smoking, many smokers are seeking new ways to quit and have made attempts to do so, without much success (Malas et al, ). This inability to quit is largely due to a dependence on nicotine (Farris et al, ; Roys et al, ). In an effort to reduce the harmful effect of tobacco, the strategy is to offer safer sources of nicotine for smokers unable or unwilling to quit (Rodu, ).…”

mentioning

confidence: 99%

E‐Cigarette Vapor Induces an Apoptotic Response in Human Gingival Epithelial Cells Through the Caspase‐3 Pathway

Rouabhia

Park

Semlali

et al. 2016

Journal Cellular Physiology

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Electronic cigarettes represent an increasingly significant proportion of today's consumable tobacco products. E-cigarettes contain several chemicals which may promote oral diseases. The aim of this study was to investigate the effect of e-cigarette vapor on human gingival epithelial cells. Results show that e-cigarette vapor altered the morphology of cells from small cuboidal form to large undefined shapes. Both single and multiple exposures to e-cigarette vapor led to a bulky morphology with large faint nuclei and an enlarged cytoplasm. E-cigarette vapor also increased L-lactate dehydrogenase (LDH) activity in the targeted cells. This activity was greater with repeated exposures. Furthermore, e-cigarette vapor increased apoptotic/necrotic epithelial cell percentages compared to that observed in the control. Epithelial cell apoptosis was confirmed by TUNEL assay showing that exposure to e-cigarette vapor increased apoptotic cell numbers, particularly after two and three exposures. This negative effect involved the caspase-3 pathway, the activity of which was greater with repeated exposure and which decreased following the use of caspase-3 inhibitor. The adverse effects of e-cigarette vapor on gingival epithelial cells may lead to dysregulated gingival cell function and result in oral disease. J. Cell. Physiol. 232: 1539-1547, 2017. © 2016 Wiley Periodicals, Inc.

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confidence: 99%

E‐Cigarette Vapor Induces an Apoptotic Response in Human Gingival Epithelial Cells Through the Caspase‐3 Pathway

Rouabhia

Park

Semlali

et al. 2016

Journal Cellular Physiology

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“…27 Although depression and tobacco use are closely linked, 53−56 depression among dual e-cigarette users has rarely been described, 27 and never for AIs. Whether ecigarettes have a causal versus mitigating effect on mood disorders deserves further study, 57,58 as does whether this effect will be greater among AI people than other racial groups, as they generally have a higher burden of mental health disorders than do whites. 59 Family medical history associated with e-cigarette use has not been assessed in other studies of dual users, although family history of lung cancer was associated with contemplating quitting smoking in one study.…”

Section: Discussionmentioning

confidence: 99%

Dual Versus Never Use of E-Cigarettes Among American Indians Who Smoke

Rhoades

Comiford

Dvorak

et al. 2019

American Journal of Preventive Medicine

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Introduction: Many American Indian communities have a high prevalence of smoking and e-cigarette use, but factors associated with their dual use are rarely studied. Methods:In 2016, a total of 375 American Indian adults who smoke completed paper surveys regarding cigarette and e-cigarette use and provided saliva for cotinine levels. In 2018, cross-sectional analyses were performed, comparing dual users (12%), defined as using e-cigarettes on some or every day for the past 30 days, with never users of e-cigarettes (37%).Results: Compared with never users, dual users were younger, more often reported history of depression (56% and 29%, respectively; p<0.01) and family history of smoking-related disease (77% and 59%, respectively; p<0.05), had lower harm perceptions of e-cigarettes (27% and 47%, respectively; p<0.01) or vapor (14% and 35%, respectively; p<0.01), and more often perceived e-cigarettes as cessation aids (75% and 16%, respectively; p<0.01) and as less harmful than cigarettes (70% and 17%, respectively; p<0.01). Dual users were less often uncertain/unknowing about e-cigarette benefits or harms (p<0.01) and more often reported likelihood to quit smoking (49% and 24%, respectively; p<0.01) and prior attempt to quit smoking, ever (89% and 67%, respectively; p<0.01) or in the past year (55% and 32%, respectively; p=0.01). Cigarette consumption and cotinine levels did not differ between groups. Dual users more often tried other nicotine products (p<0.02) and more often lived with a vaping partner/spouse (45% and 6%, respectively; p<0.01).Conclusions: Dual users perceived e-cigarettes as less harmful than cigarettes and more as cessation aids than cigarette-only users did, but cigarette consumption did not differ between groups. Whether e-cigarettes will reduce smoking-related disparities among American Indian people remains undetermined.Am J Prev Med 2019;57(3):e59−e68.

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“…Los resultados coinciden con diferentes estudios (Goodwin et al, 2011;Leventhal et al, 2007;Luk & Tsoh, 2010;Nakajima & al'Absi, 2012;Pang et al, 2015;Roys et al, 2016;Schleicher et al, 2009;Weinberger & McKee, 2012;Xu et al, 2008) en los que se muestra una asociación significativa entre la sintomatología depresiva y el afecto negativo en mujeres adultas y el nivel de dependencia. Sin embargo, los resultados obtenidos en el presente estudio incluyen la ansiedad como una variable que también se asocia con el patrón de consumo y al nivel de dependencia de la nicotina.…”

Section: Discusión Y Conclusionesunclassified

“…En cuanto a los factores asociados con el mantenimiento del consumo de tabaco en mujeres adultas, se identifican síntomas de depresión y ansiedad, así como un alto afecto negativo (Goodwin, Pagura, Spiwak, Lemeshow, & Sareen, 2011;Leventhal et al, 2007;Luk & Tsoh, 2010;Nakajima & al'Absi, 2012;Roys, Weed, Carrigan, & MacKillop, 2016). Se sabe que la comorbilidad de ansiedad y depresión es un factor que aumenta la probabilidad del consumo de sustancias, particularmente en el caso del consumo de tabaco en mujeres (Dahne, Hoffman, & MacPherson, 2015).…”

Section: Introductionunclassified

Ansiedad, depresión, afecto negativo y positivo asociados con el consumo de tabaco en universitarias

Mandujano¹,

Piña²,

Lauriano³

et al. 2018

RIIAD

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Introducción: en los últimos años, la prevalencia del consumo de tabaco en mujeres se ha incrementado de manera significativa a nivel nacional e internacional. Esto genera altos costos a nivel económico, familiar y de salud. Un sector de la población en el que resulta particularmente indispensable realizar investigación sobre los factores asociados con el consumo de tabaco es el de mujeres universitarias, a fin de incidir en el desarrollo de estrategias de prevención y en las intervenciones para dejar de fumar. Objetivo: determinar la asociación, entre el consumo de tabaco, la dependencia de la nicotina y enfermedades como ansiedad, depresión y afecto negativo y positivo en universitarias. Método: 72 universitarias fumadoras que asistieron de manera voluntaria a solicitar tratamiento para dejar de fumar al Centro de Atención y Orientación para Estudiantes (CAOPE) de la Facultad de Estudios Superiores Iztacala, de la Universidad Autónoma de México; se aplicaron diferentes instrumentos para conocer el patrón de consumo, el nivel de dependencia, la sintomatología depresiva y de ansiedad, y los afectos positivo y negativo. Resultados: todos los factores emocionales (ansiedad, depresión, afectos positivo y negativo) integrados en un modelo son predictores, tanto del patrón del consumo como del nivel de dependencia en universitarias; la ansiedad, en específico, aumenta el riesgo de consumo de tabaco y de presentar dependencia de la nicotina. Discusión y conclusiones: dichos resultados se deben considerar para diseñar estrategias de prevención y tratamiento para dejar de fumar en mujeres universitarias, en las que se incluyan técnicas cognitivo-conductuales. En cuanto a la prevención, es indispensable incluir estrategias enfocadas al autocontrol de emociones, a la solución de problemas y al afrontamiento para el manejo de la ansiedad.

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Associations between nicotine dependence, anhedonia, urgency and smoking motives

Cited by 65 publications

References 37 publications

E‐Cigarette Vapor Induces an Apoptotic Response in Human Gingival Epithelial Cells Through the Caspase‐3 Pathway

E‐Cigarette Vapor Induces an Apoptotic Response in Human Gingival Epithelial Cells Through the Caspase‐3 Pathway

Dual Versus Never Use of E-Cigarettes Among American Indians Who Smoke

Ansiedad, depresión, afecto negativo y positivo asociados con el consumo de tabaco en universitarias

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