Associations between smoking habits and major adverse cardiovascular events in patients who underwent coronary computed tomography angiography as screening for coronary artery disease

Higashi, Sara; Shiga, Yuhei; Yano, Masataka; Imaizumi, Tomoki; Tashiro, Kohei; Idemoto, Yoshiaki; Kato, Yuta; Kuwano, Takashi; Sugihara, Makoto; Miura, Shin‐ichiro

doi:10.1007/s00380-020-01727-5

Cited by 4 publications

(2 citation statements)

References 38 publications

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“…We assessed coronary artery stenosis by CCTA as previously described [8][9][10][11][12][13][14]. Coronary arteries were divided into 15 lesions for classification.…”

Section: Assessment Of Coronary Artery Stenosis By Cctamentioning

confidence: 99%

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Association Between Major Adverse Cardiovascular Events and the Gensini Score or Coronary Artery Calcification Score in Hypertensive Patients Who Have Undergone Coronary Computed Tomography Angiography

et al. 2023

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Background: From the Fukuoka University Coronary Computed Tomography Angiography (FU-CCTA) registry, we present major adverse cardiovascular events (MACEs) in hypertensive patients who have undergone CCTA, and the association between MACEs and the Gensini score of coronary arteries or the coronary artery calcification (CAC) score. Methods:Of the patients who underwent CCTA for coronary artery disease (CAD) screening at Fukuoka University Hospital, 318 hypertensive patients who had at least one cardiovascular risk factor or suspected CAD were enrolled. The patients were divided into two groups: MACEs and non-MACEs groups. The severity of atherosclerosis of coronary arteries was assessed by the Gensini score. The CAC score was also defined by computed tomography (CT) images at the time of CCTA. A primary endpoint was MACEs (all-cause death, ischemic stroke, acute myocardial infarction, coronary revascularization). The patients were followed for up to 5 years. Results:The patients were 68 ± 10 years, and 50% were males. The percentages of smoking, dyslipidemia, diabetes, and chronic kidney disease were 39%, 70%, 26% and 37%, respectively. The %males, %smoking, CAC score and Gensini score in the MACEs group were significantly higher than those in the non-MACEs group. On the other hand, the differences in age, dyslipidemia, diabetes, or chronic kidney disease between the groups were not seen. A multivariate analysis was performed regarding the presence or absence of MACE by logistic regression analysis of the CAC score or Gensini score in addition to conventional risk factors as independent variables. A Cox regression analysis revealed significant relationships for both the CAC score (P = 0.043) and the Gensini score (P = 0.008). Conclusions:The CAC score and the Gensini score could predict MACEs in hypertensive patients who have undergone CCTA.

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“…We assessed coronary artery stenosis by CCTA as previously described [8][9][10][11][12][13][14]. Coronary arteries were divided into 15 lesions for classification.…”

Section: Assessment Of Coronary Artery Stenosis By Cctamentioning

confidence: 99%

“…We have performed screening of CAD using coronary computed tomography angiography (CCTA) at Fukuoka University Hospital (FU-CCTA registry) and reported many important coronary risk factors for CAD [8][9][10][11][12][13][14]. Hypertension (HTN) is a critical coronary risk factor [15].…”

Section: Introductionmentioning

confidence: 99%