Associations of Brachial-Ankle Pulse Wave Velocity and Carotid Atherosclerotic Lesions with Silent Cerebral Lesions

Association of arterial stiffness with progression of subclinical brain and cognitive disease

“…10,11,[21][22][23][24] Consistent with these structural abnormalities, several studies have also shown PWV and CPP to be associated with cognitive function, including poorer memory and a worse performance on executive function tests. 10,11,[24][25][26][27] Much of the literature reflects cross-sectional studies, however, with fewer reports on the influence of arterial stiffness on neurovascular disease over time.…”

Silent brain infarct is independently associated with arterial stiffness indicated by cardio-ankle vascular index (CAVI)

“…21,34 Carotid intima-media thickness is also a useful and non-invasive method to examine atherosclerosis and is associated with future stroke risk. 2,3,34 There were several limitations to this study. Selection bias is possible, because this was a hospital-based cohort study, and we mainly enrolled patients who were relatively old and had cardiovascular risk factors.…”

“…8,[19][20][21][22][23][24] Arterial stiffness, as measured by conventional carotidfemoral pulse wave velocity (PWV) measurement, aortic PWV measurement or non-invasive brachial-ankle PWV (baPWV) measurement, is associated with microvascular early atherosclerotic changes and is an independent predictor for cardiovascular events and deaths. [1][2][3]7,13,14,[25][26][27][28][29] Furthermore, baPWV can be used to assess for the presence of SBI and WMHs. 7,13,14,21,30 However, the relationship between SVD and CAVI is not yet clear.…”

Brachial-ankle pulse wave velocity is associated with composite carotid and coronary atherosclerosis in a middle-aged asymptomatic population

“…Arterial stiffness has been wellknown to be associated with future cardiovascular events [11][12][13] . Previous studies have demonstrated that baPWV could be useful for screening subclinical atherosclerosis [14][15][16] . However, at present, little information is available on the relationship between these parameters and subclinical coronary and carotid atherosclerotic changes.…”