ASTROBLASTOMAS OF THE BRAIN<sup>1</sup>

Bailev, Percival; Bucy, Paul C.

doi:10.1111/j.1600-0447.1930.tb08230.x

Cited by 105 publications

(87 citation statements)

References 4 publications

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“…The histological characteristic of astroblastoma, as described by Bailey and Bucy, is the perivascular arrangement of tumor cells having thick and short cytoplasmic processes with eccentric nuclei, forming perivascular pseudorosettes [10]. The borders of the tumor more often compress, rather than infiltrate, the surrounding tissue.…”

Section: Discussionmentioning

confidence: 99%

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A case of cerebral astroblastoma with rhabdoid features: a cytological, histological, and immunohistochemical study

et al. 2015

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Section: Discussionmentioning

confidence: 99%

“…Astroblastoma is a very rare neuroepithelial tumor initially described by Bailey and Bucy in 1930 [10]. Astroblastoma accounts for 0.45-2.8% of all neuroglial tumors [11], mainly affecting children, adolescents, and young adults.…”

Section: Discussionmentioning

confidence: 99%

A case of cerebral astroblastoma with rhabdoid features: a cytological, histological, and immunohistochemical study

et al. 2015

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“…Astroblastoma is a rare type of glial tumor that was firstly described by Bailey and Buey in 1930 1 . Although its existence has been questioned by some investigators 21 , it is now recognized as a distinct clinicopathological entity 4 , probably representing less than 0.5% of gliomas 17 .…”

Section: Discussionmentioning

confidence: 99%

Complete surgical resection of high-grade astroblastoma with long time survival: case report and review of the literature

et al. 2006

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SummaryAstroblastoma is a rare glial neoplasm of unknown origin and uncertain prognosis. It usually presents in young adults as a well circumscribed hemispheric mass, often associated with a cystic component. The histological features of astroblastoma are the presence of typical astroblastic perivascular pseudorosettes and perivascular hyalinization. Two different subtypes of astroblastoma have been defined based upon histological characteristics. Prognosis, however, sometimes is in contradiction with the pathological appearance and seems to be more closely related to the grade of surgical resection. We present a new case of a patient with a high-grade astroblastoma with a long survival time, in whom complete surgical resection was confirmed by an early postoperative MRI.KEY WORDS: Astroblastoma. Glial tumor. Treatment. Prognosis.Astroblastoma de alto grado con supervivencia prolongada tras resección completa: descripción de un caso y revisión de la literatura Resumen El astroblastoma es un tumor glial infrecuente de origen desconocido y pronóstico incierto. Habitualmente se presenta en adultos como una masa hemisférica bien definida, presentando a menudo un componente quístico. Las características histopatológicas de este tumor incluyen la presencia de pseudorrosetas perivasculares astroblásticas típicas y la hialinización perivascular. Se han distinguido dos tipos de astroblastoma en relación a la malignidad histológica. Sin embargo, el pronóstico en ocasiones no guarda relación directa con el tipo histológico y parece más dependiente del grado de resección quirúrgica. Presentamos el caso de una paciente con un astroblastoma de alto grado con supervivencia prolongada, en el cual la resección quirúrgica completa se demostró mediante resonancia magnética postoperatoria precoz.

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“…It is estimated to account for 0.45-2.8% of all primary cerebral gliomas (1,30,31). Astroblastomas are initially described by Bailey and Cushing (3) and further characterized by Bailey and Bucy (2). However, much confusion has arisen regarding criteria for their diagnosis in the following years.…”

Section: █ Introductionmentioning

confidence: 99%

Astroblastoma; case report and review of literature

Barakat

Ammar²,

Salama³

et al. 2014

Turkish Neurosurgery

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ABSTRACTa gradual progressive course for the last two weeks. He presented with recurrent attacks of vomiting and confusion that rapidly worsened. Neurologically, the patient was confused and uncooperative with recurrent attacks of vomiting and bradycardia but no other neurological symptoms or signs. Computed tomography (CT) and magnetic resonance imaging (MRI) showed a well-demarcated enhancing spaceoccupying lesion, that was partially cystic, partially calcified in the subependymal area of the left frontal lobe partially projecting into the frontal horn of the lateral ventricle and causing obstructive hydrocephalus (Figure 1). We managed the patient as an urgent case in our intensive care unit (ICU) and performed urgent external ventricular drainage to manage the increased intracranial pressure (ICP). About one week later, we performed surgery for tumor resection by left frontal craniotomy. The tumor was pink-yellow in color, highly vascular, soft in consistency in parts and firm and calcified in other parts and was partially succable and well circumscribed which allowed total resection of the tumor. After the surgery, the patient ws transported routinely to the ICU for 3 days. Follow-up CT showed gross total resection (GTR) with mild postoperative brain edema at the site of surgery. The patient was followed up periodically every month for the first 3 months and then every 6 months without postoperative chemotherapy or radiotherapy and without recurrence. After one year, he showed a recurrent mass at the same site as the primary lesion in the follow-up MRI that was managed █ INTRODUCTION A stroblastoma is a rare glial tumor of the brain. It is estimated to account for 0.45-2.8% of all primary cerebral gliomas (1,30,31). Astroblastomas are initially described by Bailey and Cushing (3) and further characterized by Bailey and Bucy (2). However, much confusion has arisen regarding criteria for their diagnosis in the following years. Moreover, the origin of these tumors has been debated, because they share common histological characteristics with ependymomas and astrocytomas. Recent studies suggested that astroblastoma is a distinct histological and genetic entity (6,7,31,39). It has a distinctive characteristic of perivascular pseudorosettes with frequent vascular hyalinization. Perivascular pseudorosettes in astroblastoma have short and thick cytoplasmic processes and blunt-ended foot plates (30).We introduced a case of astroblastoma and reviewed all relevant literature of astroblastoma in order to discuss astroblastoma from the clinical, pathological, management, and prognostic view points. We tried to discover more secrets of astroblastoma and to introduce a standard approach to its diagnosis and management. █ CASE REPORTA forty-year old male patient complained of headache, nausea, vomiting, and deterioration of conscious level with Astroblastoma is a rare and distinct type of aggressive glial tumor for which there is much confusion regarding the diagnostic criteria. We present a case of astroblastoma and review...

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ASTROBLASTOMAS OF THE BRAIN¹

Cited by 105 publications

References 4 publications

A case of cerebral astroblastoma with rhabdoid features: a cytological, histological, and immunohistochemical study

A case of cerebral astroblastoma with rhabdoid features: a cytological, histological, and immunohistochemical study

Complete surgical resection of high-grade astroblastoma with long time survival: case report and review of the literature

Astroblastoma; case report and review of literature

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ASTROBLASTOMAS OF THE BRAIN1

Cited by 105 publications

References 4 publications

A case of cerebral astroblastoma with rhabdoid features: a cytological, histological, and immunohistochemical study

A case of cerebral astroblastoma with rhabdoid features: a cytological, histological, and immunohistochemical study

Complete surgical resection of high-grade astroblastoma with long time survival: case report and review of the literature

Astroblastoma; case report and review of literature

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ASTROBLASTOMAS OF THE BRAIN¹