Asymmetric modulation of human visual cortex activity during 10° lateral gaze (fMRI study)

Deutschländer, Angela; Marx, Esther; Stephan, Thomas; Riedel, Eva; Wiesmann, Martin; Dieterich, Marianne; Brandt, Thomas

doi:10.1016/j.neuroimage.2005.06.001

Cited by 27 publications

(18 citation statements)

References 58 publications

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“…The shift of the beating field leads to an asymmetric activation of the visual cortex in both hemispheres, with a stronger activation in the hemisphere contralateral to the "longer"-lasting pursuit phase. This is in agreement with a recent activation study on 10°lateral gaze compared to fixation straight ahead [Deutschländer et al, 2005]. During lateral fixation, activations occurred in the cuneus, lingual, and fusiform gyrus of the hemisphere contralateral to the fixation target.…”

Section: Discussionsupporting

confidence: 92%

Direction‐dependent visual cortex activation during horizontal optokinetic stimulation (fMRI study)

Bense

Janusch

Schlindwein

et al. 2005

Human Brain Mapping

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Looking at a moving pattern induces optokinetic nystagmus (OKN) and activates an assembly of cortical areas in the visual cortex, including lateral occipitotemporal (motion-sensitive area MT/V5) and adjacent occipitoparietal areas as well as ocular motor areas such as the prefrontal cortex, frontal, supplementary, and parietal eye fields. The aim of this functional MRI (fMRI) study was to investigate (1) whether stimulus direction-dependent effects can be found, especially in the cortical eye fields, and (2) whether there is a hemispheric dominance of ocular motor areas. In a group of 15 healthy subjects, OKN in rightward and leftward directions was visually elicited and statistically compared with the control condition (stationary target) and with each other. Direction-dependent differences were not found in the cortical eye fields, but an asymmetry of activation occurred in paramedian visual cortex areas, and there were stronger activations in the hemisphere contralateral to the slow OKN phase (pursuit). This can be explained by a shift of the mean eye position of gaze (beating field) in the direction of the fast nystagmus phases of approximately 2.6 degrees, causing asymmetrical visual cortex stimulation. The absence of a significant difference in the activation pattern of the cortical eye fields supports the view that the processing of eye movements in both horizontal directions is mediated in the same cortical ocular motor areas. Furthermore, no hemispheric dominance for OKN processing was found in right-handed volunteers.

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Section: Discussionsupporting

confidence: 92%

Direction‐dependent visual cortex activation during horizontal optokinetic stimulation (fMRI study)

Bense

Janusch

Schlindwein

et al. 2005

Human Brain Mapping

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“…This S2 response was localized to the cuneus, precuneus, and middle temporal gyrus. Due to the role of these regions in mapping eye position and integrating such information with target spatial locations (Deutschlander et al, 2005;Makino, Yokosawa, Takeda, & Kumada, 2004;Vidnyanszky, Gulyas, & Roland, 2000), this neural response difference may reflect differences in comparison of the current eye position with an endogenously generated goal location. However, if the S2 response reflects processing of the current spatial location with either the endogenously versus exogenously generated target location, it is not clear why the S2 responses for the prosaccades (exogenous goal location) and erroneous prosaccades (exogenous and endogenous goal locations) do not differ.…”

Section: Discussionmentioning

confidence: 99%

Spatio-temporal Brain Dynamics Underlying Saccade Execution, Suppression, and Error-related Feedback

Herdman

Ryan

2007

Journal of Cognitive Neuroscience

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Abstract& Human and nonhuman animal research has outlined the neural regions that support saccadic eye movements. The aim of the current work was to outline the sequence by which distinct neural regions come on-line to support goal-directed saccade execution and error-related feedback. To achieve this, we obtained behavioral responses via eye movement recordings and neural responses via magnetoencephalography (MEG), concurrently, while participants performed an antisaccade task. Neural responses were examined with respect to the onset of the saccadic eye movements. Frontal eye field and visual cortex activity distinguished subsequently successful goal-directed saccades from (correct and erroneous) reflexive saccades prior to the deployment of the eye movement. Activity in the same neural regions following the saccadic movement distinguished correct from incorrect saccadic responses. Error-related activity in the frontal eye fields preceded that from visual regions, suggesting a potential feedback network that may drive corrective eye movements. This work provides the first empirical demonstration of simultaneous remote eyetracking and MEG recording. The coupling of behavioral and neuroimaging technologies, used here to characterize dynamic brain networks underlying saccade execution and error-related feedback, demonstrates a novel within-paradigm converging evidence approach by which to outline the neural underpinnings of cognition. &

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“…Furthermore, the fusional vergence in response to a retinal disparity and the accommodative vergence affects the fixation when there is a loss of focus [2]. Previously, fixation stability has been studied during reading [19][20][21], when studying intruding saccades and nystagmus [8,22,23], and in studies using magnetic resonance imaging (MRI) [24] and position emission tomography (PET) [25].…”

Section: Introductionmentioning

confidence: 99%

Visual fixation development in children

Aring

Grönlund

Hellström

et al. 2007

Graefes Arch Clin Exp Ophthalmol

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Asymmetric modulation of human visual cortex activity during 10° lateral gaze (fMRI study)

Cited by 27 publications

References 58 publications

Direction‐dependent visual cortex activation during horizontal optokinetic stimulation (fMRI study)

Direction‐dependent visual cortex activation during horizontal optokinetic stimulation (fMRI study)

Spatio-temporal Brain Dynamics Underlying Saccade Execution, Suppression, and Error-related Feedback

Visual fixation development in children

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