Presbyopia is defined as the inability to focus on near targets, and its correction following cataract surgery remains one of the most significant challenges for ophthalmologists and cataract surgeons.1,2 According to the World Health Organization (WHO), age-related cataracts are responsible for ~48% of world blindness, equating to ~18 million people, 3 whereas presbyopia is estimated to affect over one billion individuals globally and may be universal in those aged >65 years.
4Presbyopia arises due to the age-related loss of crystalline lens accommodation, 1,5,6 but the underlying mechanisms remain enigmatic.