Asymptomatic inflammatory myofibroblastic tumor of the heart: immunohistochemical profile, differential diagnosis, and review of the literature

Febrile Illness in an Infant With an Intracardiac Inflammatory Myofibroblastic Tumor

“…ALK-1 is positive in 35% of IMTs, 11 although a negative result does not rule out the diagnosis because several intracardiac IMTs have previously stained negative. 2,8,12,13 IMTs are described as benign reactive lesions; although the exact etiology of the tumor is unknown, several studies have associated IMTs with Epstein-Barr infection. 8,[11][12][13] Listeria monocytogenes has also been reported to cause IMTs as well.…”

A Rare Case of an Inflammatory Myofibroblastic Tumor in a Middle-Aged Female

“…In some rare cases it may involve any anatomical part and may arise as late as the eighth decade of life [5, 14, 15]. However, Gleason and Hornick emphasized that the diagnosis of IMT in middle aged or elderly patients should be made with hesitance [5].…”

Cardiac Inflammatory Myofibroblastic Tumor

“…The majority of tumors are firm in consistency, with a few showing mucoid and, rarely, friable areas. Areas of cystic degeneration, Eilers et al 557 20 18 yrs M Constitutional, other IVS, RV, RVOT 3.5 IMT SR 14 21 11 mo M Cardiac RVOT, IVS, PV 2.5 IMT SR 15 22 22 yrs M Constitutional, GI IVS 8.6 IP SR 16 23 49 yrs M Cardiac, respiratory LA, MV, Pveins U IMT SR 17 24 62 yrs F Respiratory, cardiac AV, MV U IP SR 18 25 3 mo F Constitutional, cardiac LV 5.4 IMT T 19 14 5 wks M Respiratory RA 6 IMT U 20 14 2 yrs F Neurologic LV, MV 4 IMT SR 21 14 5 yrs F Neurologic LV, MV 3 IMT U 22 14 10 yrs M Cardiac RVOT 1.5 IMT U 23 14 12 yrs M Neurologic RV 6 IMT U 24 14 17 yrs F Cardiac RV, TV 5 IMT U 25 14 19 yrs F Constitutional LV 3.2 IMT SR 26 14 21 yrs F Constitutional, respiratory IVS, PV, RVOT 4 IMT SR 27 26 69 yrs F Constitutional, respiratory AV, IVS, MV 3 IMT SR 28 27 7 yrs F Cardiac TV, RVOT, PA, PV 5 IMT SR 29 28 54 yrs F A/I AV, AVS, CA, MV, TV 4.8 IP S 30 29 48 yrs F Constitutional AR, AV, PA, RVOT U IMT A, S 31 30 2 mo M Neurologic, cardiac, respiratory RV, RA, TV 2 IMT SR 32 31 2 mo F Cardiac RA 2.5 IMT SR 33 32, 33 35 yrs M Constitutional, respiratory IAS, CS, RA, RV, TV 5 PFT SR 34 34 27 yrs M Cardiac, constitutional, respiratory IVS, RV, LV, P 2.5 IP IB 35 35 13 41 13 wks M U RV 2.5 IMT SR 43 41 1 yrs M U RV 2 IMT SR 44 42 62 yrs M Syncope IAS, RA, AV 5 IP SR 45 43 3 mo F Respiratory IVS U IMT SR 46 44 5 mo F Cardiac IVS, RVOT, PV, PA 3 IMT SR 47 45 4 mo M A/I RA 5 IP SR 48 46 15 yrs M Cardiac, sudden death CA (also spleen by autopsy) U IPT N/A 49 46 5 mo F Respiratory RA, SVC, AVG 2.5 IPT SR 50 47 1 yrs 48 17 yrs M Constitutional, other IAS, IVS, RA, RV, TV U IPT SR 54 …”