Atherosclerosis and Inflammatory Heart Disease

Fairweather, De Lisa

doi:10.1007/978-1-61779-812-2_11

Cited by 1 publication

(1 citation statement)

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“…Inflammation is basically a protective response that fights the cause of cellular damage (e.g., germs or toxins) and the consequences of that damage, i.e., necrotic cells and tissues [ 1 , 2 , 3 , 4 ]. Inflammation causes hypersensitivity reactions to insect bites, drugs, and toxins, as well as some chronic diseases, such as rheumatoid arthritis, atherosclerosis, and pulmonary fibrosis [ 5 , 6 , 7 , 8 ]. Inflammation is a complex process that begins with tissue damage caused by endogenous factors, such as tissue necrosis and bone fractures, or exogenous factors, such as mechanical, physical, biological damage (like infection with microorganisms or immunological responses, such as hypersensitivity reactions), and is accompanied by the invasion of inflammatory cells into the inflamed area [ 9 , 10 ].…”

Section: Introductionmentioning

confidence: 99%

Recent Advances in Inflammatory Diagnosis with Graphene Quantum Dots Enhanced SERS Detection

et al. 2022

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Inflammatory diseases are some of the most common diseases in different parts of the world. So far, most attention has been paid to the role of environmental factors in the inflammatory process. The diagnosis of inflammatory changes is an important goal for the timely diagnosis and treatment of various metastatic, autoimmune, and infectious diseases. Graphene quantum dots (GQDs) can be used for the diagnosis of inflammation due to their excellent properties, such as high biocompatibility, low toxicity, high stability, and specific surface area. Additionally, surface-enhanced Raman spectroscopy (SERS) allows the very sensitive structural detection of analytes at low concentrations by amplifying electromagnetic fields generated by the excitation of localized surface plasmons. In recent years, the use of graphene quantum dots amplified by SERS has increased for the diagnosis of inflammation. The known advantages of graphene quantum dots SERS include non-destructive analysis methods, sensitivity and specificity, and the generation of narrow spectral bands characteristic of the molecular components present, which have led to their increased application. In this article, we review recent advances in the diagnosis of inflammation using graphene quantum dots and their improved detection of SERS. In this review study, the graphene quantum dots synthesis method, bioactivation method, inflammatory biomarkers, plasma synthesis of GQDs and SERS GQD are investigated. Finally, the detection mechanisms of SERS and the detection of inflammation are presented.

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