Atmospheric pressure plasma jet for biomedical applications characterised by passive thermal probe

Mance, Diana; Wiese, Ruben; Kewitz, Thorben; Kersten, Holger

doi:10.1140/epjd/e2018-80768-8

Cited by 16 publications

(11 citation statements)

References 35 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…At still larger distances (>1000 µm) radiation represents the most dominant part of the transferred energy due to its larger range. This behavior was already reported for atmospheric pressure discharges in previous studies [24,25].…”

Section: Influence Of Substrate (Ptp) Distancesupporting

confidence: 87%

“…particle impact, surface processes as recombination, radiation [16]) and influences film growths and particle formation processes [17][18][19][20] as well as surface cleaning and surface activation. With increasing application of atmospheric pressure plasmas successful attempts were made to adapt the diagnostic also to atmospheric pressure plasma jets with high energy fluxes for industrial use [21][22][23] and for non-equilibrium plasma jets which are used for biomedical applications [24,25].…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Energy flux measurements on an atmospheric pressure surface barrier discharge

Hansen¹,

Reck²,

Kersten³

2019

J. Phys. D: Appl. Phys.

Self Cite

View full text Add to dashboard Cite

Energy flux measurements by a passive thermal probe were performed for a diffuse coplanar surface barrier discharge to determine the transfered energy to a substrate in dependence on the substrate distance to the electrode and working gas of the discharge. The largest energy flux was found at ∼300–400 m above the electrode surface to be about 900 mW cm−2. Furthermore, an active substrate cooling mechanism could be identified within the plasma caused by gas convection flows for very small distances. Variation of the working gas (argon, molecular gas) indicates the importance of the gas and surface reactivity for the transferred energy to the substrate. Molecular gases result in a remarkably higher energy flux compared to rare gas.

show abstract

Section: Influence Of Substrate (Ptp) Distancesupporting

confidence: 87%

Section: Introductionmentioning

confidence: 99%

Energy flux measurements on an atmospheric pressure surface barrier discharge

Hansen¹,

Reck²,

Kersten³

2019

J. Phys. D: Appl. Phys.

Self Cite

View full text Add to dashboard Cite

show abstract

“…[ 37,38 ] One of the most important factors for the transfer of thermal energy from APPJ plumes is the distance to the substrate. [ 39 ] For the purposes of this study, maximizing treatment intensity, with slower treatment speeds, was more important than minimizing morphological changes. In fact, morphological changes on MEW meshes had little or no effect on microfiber mesh load‐carrying ability as demonstrated by the uniaxial tensile test.…”

Section: Discussionmentioning

confidence: 99%

Covalent Protein Immobilization on 3D‐Printed Microfiber Meshes for Guided Cartilage Regeneration

Ainsworth

Lotz

Gilmour

et al. 2022

Adv Funct Materials

View full text Add to dashboard Cite

Current biomaterial-based strategies explored to treat articular cartilage defects have failed to provide adequate physico-chemical cues in order to guide functional tissue regeneration. Here, it is hypothesized that atmospheric-pressure plasma (APPJ) treatment and melt electrowriting (MEW) will produce microfiber support structures with covalently-immobilized transforming growth factor beta-1 (TGFβ1) that can stimulate the generation of functional cartilage tissue. The effect of APPJ operational speeds to activate MEW polycaprolactone meshes for immobilization of TGFβ1 is first investigated and chondrogenic differentiation and neo-cartilage production are assessed in vitro. All APPJ speeds test enhanced hydrophilicity of the meshes, with the slow treatment speed having significantly less CC/CH and more COOH than the untreated meshes. APPJ treatment increases TGFβ1 loading efficiency. Additionally, in vitro experiments highlight that APPJ-based TGFβ1 attachment to the scaffolds is more advantageous than direct supplementation within the medium. After 28 days of culture, the group with immobilized TGFβ1 has significantly increased compressive modulus (more than threefold) and higher glycosaminoglycan production (more than fivefold) than when TGFβ1 is supplied through the medium. These results demonstrate that APPJ activation allows reagentfree, covalent immobilization of TGFβ1 on microfiber meshes and, importantly, that the biofunctionalized meshes can stimulate neo-cartilage matrix formation. This opens new perspectives for guided tissue regeneration.

show abstract

“…For decades non-equilibrium plasmas operating at low pressures have been used in various applications due to their rich chemistry [35,37,[50][51][52][53]. Thus, cold atmospheric plasmas technologies have been considered a viable alternative to low-pressure plasma mainly due to the numerous applications that include samples that cannot undergo a vacuum [36,38,[54][55][56][57][58][59][60][61][62][63][64][65]. However, ignition and sustaining of cold atmospheric pressure plasmas are more challenging due to the considerably higher breakdown voltage and set of parameters usually falling in the unfavorable region of Paschen's curve [43,63,[66][67][68].…”

Section: Introductionmentioning

confidence: 99%

Cold atmospheric plasma technology for removal of organic micropollutants from wastewater—a review

et al. 2021

View full text Add to dashboard Cite

Water bodies are being contaminated daily due to industrial, agricultural and domestic effluents. In the last decades, harmful organic micropollutants (OMPs) have been detected in surface and groundwater at low concentrations due to the discharge of untreated effluent in natural water bodies. As a consequence, aquatic life and public health are endangered. Unfortunately, traditional water treatment methods are ineffective in the degradation of most OMPs. In recent years, advanced oxidation processes (AOPs) techniques have received extensive attention for the mineralization of OMPs in water in order to avoid serious environmental problems. Cold atmospheric plasma discharge-based AOPs have been proven a promising technology for the degradation of non-biodegradable organic substances like OMPs. This paper reviews a wide range of cold atmospheric plasma sources with their reactor configurations used for the degradation of OMPs (such as organic dyes, pharmaceuticals, and pesticides) in wastewater. The role of plasma and treatment parameters (e.g. input power, voltage, working gas, treatment time, OMPs concentrations, etc.) on the oxidation of various OMPs are discussed. Furthermore, the degradation kinetics, intermediates compounds formed by plasma, and the synergetic effect of plasma in combination with a catalyst are also reported in this review. GraphicAbstract

show abstract

Atmospheric pressure plasma jet for biomedical applications characterised by passive thermal probe

Cited by 16 publications

References 35 publications

Energy flux measurements on an atmospheric pressure surface barrier discharge

Energy flux measurements on an atmospheric pressure surface barrier discharge

Covalent Protein Immobilization on 3D‐Printed Microfiber Meshes for Guided Cartilage Regeneration

Cold atmospheric plasma technology for removal of organic micropollutants from wastewater—a review

Contact Info

Product

Resources

About