Atomic spectrometry update: review of advances in the analysis of clinical and biological materials, foods and beverages

Taylor, Andrew M.; Barlow, Nicola; Day, Martin P.; Hill, Sarah; Patriarca, Marina; White, Mark A.

doi:10.1039/c6ja90005d

Cited by 15 publications

(3 citation statements)

References 164 publications

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“…A multiplex and accurate technique for biomolecule quantification plays an important role in the elucidation of molecular mechanisms and early diagnosis for many diseases because living bodies are complicated assemblies of multiple biomolecules that interact with each other to achieve different physiological states. Complementary to the mainstream fluorescent tagging that is often limited by molecular spectral overlapping, metal stable isotope tagging has demonstrated great and unique success in the multiplex and accurate quantification of proteins, − enzymes, , small molecules, nucleic acids, − and single cells, − thanks to the excellent mass spectral resolution, wide dynamic ranges of 9 orders of magnitude, low matrix effect, and high metrological value for absolute quantification. − For instance, Nolan et al simultaneously detected 34 parameters in single cells using polymer lanthanide isotopes as tags, and the assay provided a systematic view of the immune signal in human hematopoietic cells . Zhang et al.…”

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confidence: 99%

Lanthanide Nanoprobes for the Multiplex Evaluation of Breast Cancer Biomarkers

Chen

Song

et al. 2021

Anal. Chem.

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Metal stable isotope tagging has demonstrated great and unique success in the multiplex and ratiometry-based accurate detection of biomolecules and single cells, while its sensitivity is regarded as an Achilles' heel. Although lanthanide nanoparticles remain the most promising tags for elemental mass spectrometry, there is no report on the lanthanide nanoparticle-based multiplex immunoassay of disease markers in clinical serum samples because of their tough synthesis and bioconjugation and a complex physiological sample matrix. Herein, to fill this gap, multiple lanthanide nanoparticle tags (NaEuF 4 , NaTbF 4 , and NaHoF 4 ) were delicately designed and facilely synthesized with a one-pot solvothermal method for the multiplex evaluation of breast cancer biomarkers carcinoembryonic antigen (CEA), CA153, and CA125 in human serum samples. The proposed method exhibited wide linear ranges and low levels of the detection limit for all biomarkers. The test results were consistent with the routine electrochemiluminescence results in clinical serum samples, which proved the possibility of the early prognosis of breast cancer as well as improving the surgical outcome prediction.

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confidence: 99%

Lanthanide Nanoprobes for the Multiplex Evaluation of Breast Cancer Biomarkers

Chen

Song

et al. 2021

Anal. Chem.

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“…The Zn recovery efficiency was determined on the basis of XRF results obtained for the powdered raw materials, residues, and precipitates. The results of the elemental analyses were produced by the validated XRF method capable of analyzing quantitatively diverse samples [13].…”

Section: Discussionmentioning

confidence: 99%

Selective Recovery of Zinc from Metallurgical Waste Materials from Processing Zinc and Lead Ores

Hyk

Kitka

Rudnicki³

2019

Molecules

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A method for processing of metallurgical waste materials (chemically defined as sulfur-bearing zinc-ferric materials) produced by plants processing zinc ores and their concentrates is proposed. The method proposed is a combination of pyro- and hydrometallurgical treatments of the waste material. The crucial steps in the developed method include: roasting the material at 450 °C to generate sulfur dioxide (SO2), absorption of SO2 in an aqueous system to form sulfuric acid (IV), carbothermic decomposition of zinc ferrite compounds, and leaching of zinc from the roasted material using sulfuric (IV) acid. The method allows one to extract up to 40% of zinc from the waste material and, consequently, to generate a fraction of material with substantially higher content of iron oxides. The proposed method takes advantage of the presence of sulfur in the processed material which upon roasting is converted to sulfuric acid (IV)—a leaching agent for selective extraction of zinc. The properly adjusted pH of the aqueous medium in which the leaching process is carried out is the key factor determining the quantitative and selective separation of zinc. If the amount of sulfur in the processed material is insufficient, it may be supplemented by adding sulfuric acid (VI) to adjust the pH. The method proposed was tested at a laboratory scale and quarter industrial scale using the real samples taken from stockpiles in the vicinity of the plant processing zinc and lead ores in Poland. It may also work for any zinc-ferric materials from various sources.

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“…Some other general reviews of element speciation provide broad information on arsenic speciation, including analytical methodology and types of food. 77,[88][89][90][91][92] Moreover, the importance of maintaining the integrity of arsenic species during the overall analytical process, with final measurement using HPLC-ICP-MS and hydride generation-atomic fluorescence spectrometry (HG-AFS), is emphasized widely in a recent review. 93 Efforts have also been made in the last decades by research scientists, government agencies (FDA and EPA), and commercial laboratories to establish methodologies for the specific determination of iAs in food products.…”

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Inorganic Arsenic Determination in Food: A Review of Analytical Proposals and Quality Assessment Over the Last Six Years

2016

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Here we review recent developments in analytical proposals for the assessment of inorganic arsenic (iAs) content in food products. Interest in the determination of iAs in products for human consumption such as food commodities, wine, and seaweed among others is fueled by the wide recognition of its toxic effects on humans, even at low concentrations. Currently, the need for robust and reliable analytical methods is recognized by various international safety and health agencies, and by organizations in charge of establishing acceptable tolerance levels of iAs in food. This review summarizes the state of the art of analytical methods while highlighting tools for the assessment of quality assessment of the results, such as the production and evaluation of certified reference materials (CRMs) and the availability of specific proficiency testing (PT) programmes. Because the number of studies dedicated to the subject of this review has increased considerably over recent years, the sources consulted and cited here are limited to those from 2010 to the end of 2015.

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Atomic spectrometry update: review of advances in the analysis of clinical and biological materials, foods and beverages

Abstract: This 2016 review discusses developments in elemental mass spectrometry, atomic absorption, emission and fluorescence, XRF and LIBS, as applied to the analysis of specimens of clinical interest, foods and beverages. Sample preparation procedures and quality assurance are also included.

Cited by 15 publications

References 164 publications

Lanthanide Nanoprobes for the Multiplex Evaluation of Breast Cancer Biomarkers

Lanthanide Nanoprobes for the Multiplex Evaluation of Breast Cancer Biomarkers

Selective Recovery of Zinc from Metallurgical Waste Materials from Processing Zinc and Lead Ores

Inorganic Arsenic Determination in Food: A Review of Analytical Proposals and Quality Assessment Over the Last Six Years

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