Atorvastatin — 20 Years in the Struggle for Life

Gogolashvili, N. G.

doi:10.15829/1560-4071-2018-2-134-149

Cited by 4 publications

(2 citation statements)

References 101 publications

(123 reference statements)

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“…Возможности аторвастатина снижать риски неблагоприятных сердечно-сосудистых событий активно изучались в течение последних 25 лет как в сравнении с плацебо, так и в сравнении с другими статинами [38,39]. Большое количество исследований было проведено в группах пациентов с различными АССЗ [40][41][42][43][44].…”

Section: исследования по влиянию на клинические исходыunclassified

Moderate-intensity statin therapy. Efficacy and safety issues

Gogolashvili

2023

Russ J Cardiol

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High rates of cardiovascular (CV) morbidity and mortality dictates the need to determine approaches to therapy that would reduce complications rate and improve patient’s prognosis. High-intensity statin therapy is an integral part of the treatment of patients with high and very high cardiovascular risk. At the same time, there is a large cohort of patients who would benefit from moderate intensity statin therapy. In the present article we have summarized available data on hypolipidemic effects, pleiotropic effects and role of moderate intensity statin therapy, atorvastatin particularly, in reding the risk of major adverse cardiac events.

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Section: исследования по влиянию на клинические исходыunclassified

Moderate-intensity statin therapy. Efficacy and safety issues

Gogolashvili

2023

Russ J Cardiol

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“…In the ARMYDA study, patients (n=153) were randomised into the group with 40mg/day atorvastatin intake and the placebo group 7 days prior to elective PCI. The frequency of perioperative MI was 5% among patients receiving atorvastatin one week prior to PCI and 18% in the placebo group (р=0.025) [30]. The NAPLES (Novel Approaches for Preventing or Limiting Events) study, which enrolled 668 patients, had a slightly different design.…”

Section: Modifi Able Risks Before Elective Pci: Prognostic Signifi Camentioning

confidence: 99%

Preparation of Patients for Elective Percutaneous Coronary Intervention: Management of Risk Factors as an Approach to Increase in Intervention Efficacy

et al. 2019

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The article is a topical literature review of the place of percutaneous coronary interventions in the structure of elective revascularisation procedures, preoperative preparation of patients with stable ischaemic heart disease before percutaneous coronary intervention, the prospects of the technique, taking into account the latest advances in intervention cardiology (intravascular methods for assessing the hemodynamic significance of stenosis, drug eluting stents). Modern data of the early and long-term results of percutaneous coronary intervention are presented, the predictable potentially modifiable risks of adverse events are described, and ways to correct them are discussed. The results of randomised studies comparing the effectiveness of different approaches for managing patients with stable coronary heart disease (medical therapy, percutaneous coronary intervention) are presented, and prospects for using new drugs to improve the early and late outcomes of endovascular revascularisation are discussed.

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