Atrial Fibrillation and Mitral Valve Prolapse

Borger, Michael A.; Mansour, Moussa; Levine, Robert A.

doi:10.1016/j.jacc.2018.11.018

Cited by 15 publications

(14 citation statements)

References 33 publications

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“…However, to the best of our knowledge, no study has demonstrated the presence of an inflammatory component in MVP confirmed by histopathological analysis. In addition, regional myocardial 18 F-FDG uptake is not specific to inflammation since it can also reflect myocardial ischemia, as the study authors indicated (27).…”

mentioning

confidence: 88%

“…Moreover, mitral insufficiency is the most frequent complication of MVP. This condition can cause atrial dilatation, which can be associated with atrial fibrillation (18). Atrial dilatation promotes the development of supraventricular arrhythmias.…”

mentioning

confidence: 99%

“…Another complication in the interpretation of 18 F-FDGPET findings is that an inadequate suppression of physiologic myocardial uptake of 18 F-FDG may lead to false positive results. Moreover, a selective FDG uptake in the left ventricle inferolateral wall is considered a normal physiologic pattern (24).…”

mentioning

confidence: 99%

“…Moreover, a selective FDG uptake in the left ventricle inferolateral wall is considered a normal physiologic pattern (24). In this setting, to improve the specificity, 18 F-FDGPET results should be compared with T2-weighted CMR images to detect myocardial edema, and with LGE images to detect myocardial injury/fibrosis. However, Miller et al did not compare FDG uptake with T2-weighted images in their study.…”

mentioning

confidence: 99%

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Mitral valve prolapse imaging: the role of tissue characterization

Pradella¹,

Grazzini²,

Miele³

2020

Quant Imaging Med Surg

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confidence: 88%

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confidence: 99%

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confidence: 99%

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confidence: 99%

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Mitral valve prolapse imaging: the role of tissue characterization

Pradella¹,

Grazzini²,

Miele³

2020

Quant Imaging Med Surg

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“…AF is a common sequela of degenerative mitral regurgitation (DMR) and it can lead to progressive left ventricular failure if untreated [27]. DMR may lead to the development of AF via left atrial (LA) volume and pressure overload, progressive atrial fibrosis, LA enlargement, and electroanatomic remodeling [2,27].…”

Section: Af and Mitral Regurgitationmentioning

confidence: 99%

Mutual relationship between heart failure and atrial fibrillation

Sarullo

Schembri

Nugara

et al. 2020

Monaldi Arch Chest Dis

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Atrial fibrillation (AF) and heart failure (HF) are evolving epidemies, together responsible for substantial human suffering and health-care expenditure. The simultaneous co-hexistence of the two conditions is associated with mortality rates higher than those observed in individuals with only one or none of them. Patients with concomitant HF and AF suffer from even worse symptoms and poorer prognosis, yet evidence-based evaluation and management of this group of patients is lacking. In this review, we evaluate the common mechanisms for the development of AF in HF patients and vice versa, focusing on the evidence for potential treatment strategies. Recent data have suggested that these patients may respond differently if compared to those with HF or AF alone. These results highlight the clear clinical need to identify and treat these diseases according to best evidence, in order to prevent adverse outcomes and reduce the huge burden that HF and AF are expected to have on global healthcare systems in the future.

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