Atropine in Keratoplasty for Keratoconus

Geyer, Orna; Rothkoff, L; Lazar, Moshé

doi:10.1097/00003226-199109000-00002

Cited by 12 publications

(3 citation statements)

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“…Mydriatic instillation during and after the procedure was reportedly performed in a quarter of patients, including the cases originally described by Urrets-Zavalia. Our observations, in corroboration with those of other authors, indicate atropine does not increase the risk of UZS development (32,(44)(45) . In fact, it is questionable whether the use of these measures prevents iris injury (13) .…”

Section: Discussionsupporting

confidence: 93%

Update and review of Urrets-Zavalia syndrome

Magalhaes¹,

Kronbauer²,

Müller³

et al. 2016

Arquivos Brasileiros De Oftalmologia

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Section: Discussionsupporting

confidence: 93%

Update and review of Urrets-Zavalia syndrome

Magalhaes¹,

Kronbauer²,

Müller³

et al. 2016

Arquivos Brasileiros De Oftalmologia

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“…Urrets-Zavali [ 1 ] believes that the use of atropine during surgery causes the iris to make contact with the peripheral cornea, leading to peripheral anterior synechiae and secondary glaucoma. However, a prospective study by Geyer et al [ 18 ] in 1991 concluded that the occurrence of UZS after keratoplasty was not associated with the use of atropine.…”

Section: Discussionmentioning

confidence: 99%

Risk Factors of Urrets-Zavalia Syndrome after Penetrating Keratoplasty

Wang

Gao

et al. 2022

JCM

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Objective: The objective of this study was to analyze the clinical features and risk factors of Urrets-Zavalia syndrome (UZS) after penetrating keratoplasty (PKP). Methods: The medical records of 152 patients who underwent PKP at the Department of Ophthalmology, Tongji Hospital, between January 2014 and December 2016 were retrospectively reviewed. UZS was diagnosed based on pre- and post-operative pupillary findings. The relationships among the primary disease, postoperative intraocular pressure (IOP), and the incidence of UZS were statistically analyzed. The pupillary changes during the follow-up period were studied. Results: Among the 152 included patients, 23 were diagnosed with UZS, with an incidence of 15.13%. The primary diseases of the UZS patients were keratoconus (eight cases, 34.78%), viral keratitis (six cases, 26.08%), leukoma (four cases, 17.39%), fungal corneal ulcer (two cases, 8.70%), corneal endothelial decompensation (two cases, 8.70%), and corneal degeneration (one case, 4.35%). The incidence of UZS in keratoconus patients was higher than that in patients with fungal corneal ulcer (42.11% versus 6.25%, p = 0.003); In addition, the transient postoperative high IOP was not significantly related to the incidence of UZS in keratoconus patients in our study (p = 0.319). Twenty-one patients with UZS were followed up for >6 months, seven of whom (33.33%) recovered spontaneously (within the range of 48 days to 1.5 years). Conclusion: In our study, the incidence of UZS after PKP was 15.13%, and 33.33% of these patients recovered spontaneously. UZS may be more likely to occur in patients with keratoconus. Postoperative transient high IOP may increase the incidence of UZS after PKP for keratoconus.

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“…They were originally thought to play a major role in the development of the condition; however, several reports questioned this association, claiming that mydriatics play no role in the pathogenesis of UZS. 23,24 Some authors encourage the use of postoperative strong mydriatics because they may protect against this complication. 25,26 The implantation surgery in our patient was performed under topical anesthesia and was uneventful.…”

Section: Discussionmentioning

confidence: 99%

Urrets-Zavalia syndrome after implantable Collamer lens placement

2015

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SummaryWe describe the case of a healthy 28-year-old woman who underwent implantation of a posterior chamber, phakic, toric, implantable Collamer lens (ICL) in both eyes for correction of bilateral high myopia with astigmatism. On the first postoperative day the patient developed increased intraocular pressure (IOP) and a fixed, mid-dilated pupil in her left eye. The elevated IOP was corrected within 3 days by medical treatment. However, the pupil remained mid-dilated and nonreactive to both light and accommodative effort during 2 months of follow-up; there was no reaction to pilocarpine (0.125% or 4%) eyedrops. The patient was diagnosed with Urrets-Zavalia syndrome (UZS), which has been reported in association with ICL implantation only once previously.

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Atropine in Keratoplasty for Keratoconus

Cited by 12 publications

References 0 publications

Update and review of Urrets-Zavalia syndrome

Update and review of Urrets-Zavalia syndrome

Risk Factors of Urrets-Zavalia Syndrome after Penetrating Keratoplasty

Urrets-Zavalia syndrome after implantable Collamer lens placement

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