Attenuated Low‐Grade Inflammation Following Long‐Term Dietary Intervention in Postmenopausal Women with Obesity

Blomquist, Caroline; Alvehus, Malin; Burén, Jonas; Ryberg, Mats; Larsson, Christel; Lindahl, Bernt; Mellberg, Caroline; Söderström, Ingegerd; Chorell, Elin; Olsson, Tommy

doi:10.1002/oby.21815

Cited by 18 publications

(53 citation statements)

References 41 publications

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“… Estimated food records during 4 days at baseline, 6 months and 24 months. Blomquist C, et al 2018 [ 44 ] Centesimal composition: Not informed. Included: lean meat, fish, eggs, vegetables, fruits, nuts, avocado, rapeseed oil and olive oil.…”

Section: Resultsmentioning

confidence: 99%

“…The three markers were evaluated in five studies [ 23 , 26 , 27 , 30 , 37 ]; weight and WC were evaluated in three studies [ 40 , 41 , 44 ], and weight only was evaluated in three other studies [ 14 , 42 , 43 ].…”

Section: Resultsmentioning

confidence: 99%

“…Among the articles in which was performed the meta-analysis, five (45,5%) involved women mostly in the menopausal or postmenopausal period, and was evaluated the effect of diet on weight loss [ 23 , 26 , 27 , 43 , 44 ]. There was an article on healthy women with a focus on disease prevention [ 41 ].…”

Section: Resultsmentioning

confidence: 99%

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Influence of Paleolithic diet on anthropometric markers in chronic diseases: systematic review and meta-analysis

Menezes

Sampaio

Carioca

et al. 2019

Nutr J

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Background The Paleolithic diet has been studied in the scope of prevention and control of chronic noncommunicable diseases (CNCD). The objective of this study was to analyze the influence of the Paleolithic diet on the prevention and control of CNCD in humans, specifically on anthropometric markers, through a systematic review with meta-analysis. Methods What is the effect of the Paleolithic diet on anthropometric parameters (weight, body mass index and waist circumference) compared to other control diets based on recommendations in adults? We included only randomized studies with humans that used the Paleolithic Diet in the prevention and control of CNCD published in Portuguese, English or Spanish. The search period was until March 2019, in the LILACS, PubMed, Scielo, Science Direct, Medline, Web of Science and Scopus databases. The abstracts were evaluated by two researchers. We found 1224 articles, of which 24 were selected and 11 were included in the meta-analysis. The effect of dietary use on body weight, body mass index and waist circumference was evaluated. Results The summary of the effect showed a loss of − 3.52 kg in the mean weight (CI 95%: − 5.26; − 1.79; p < 0,001; I 2 = 24%) of people who adopted the Paleolithic diet compared to diets based on recommendations. The analysis showed a positive association of adopting the Paleolithic diet in relation to weight loss. The effect was significant on weight, body mass index and waist circumference. Conclusion The Paleolithic diet may assist in controlling weight and waist circumference and in the management of chronic diseases. However, more randomized clinical studies with larger populations and duration are necessary to prove health benefits. Trial registration CRD42015027849 .

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

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Influence of Paleolithic diet on anthropometric markers in chronic diseases: systematic review and meta-analysis

Menezes

Sampaio

Carioca

et al. 2019

Nutr J

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show abstract

“…Study selection: The electronic search on literature yielded 2722 titles, of which 26 were reviewed in full text considering the criteria of eligibility. Of these studies, 19 papers were excluded for the following reasons: 1) seven studies reported no data related to our target outcomes (Baumgartner et al, 2009, Frassetto et al, 2013, Genoni et al, 2016a, Jonsson et al, 2010, Jonsson et al, 2013, Lee et al, 2017, Singh et al, 2012; 2) six studies reported duplicated results (Andersson et al, 2016, Blomquist et al, 2017a, Blomquist et al, 2017b, Boraxbekk et al, 2015, Sandberg et al, 2012, Stomby et al, 2015; 3) four studies had single-arm design with no control group (Frassetto et al, 2009, Osterdahl et al, 2008, Ryberg et al, 2013, Trexler et al, 2013; 4) one study evaluated the effect of PD along with exercise (Otten et al, 2016b); and 5) one study evaluated the acute effects of following the PD consumption (Bligh et al, 2015). In addition, one additional study (Mellberg et al, 2014) was added after the manual search of references.…”

Section: Resultsmentioning

confidence: 99%

Effects of Paleolithic Diet on Glucose Control in Adults: A Systematic Review and Meta-analysis of Controlled Clinical Trials

Mohammadi

Ghaedi

et al. 2019

JNFS

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Background: Although the results were conflicting, the Paleolithic diet (PD) was proposed to be effective in improvement of metabolic status. We aimed to conduct a systematic review and meta-analysis on the randomized controlled clinical trials (RCTs) evaluating the effects of PD on glycemic markers. Methods: Online databases such as PubMed, Scopus, Web of Science, and Google Scholar were searched up to December 2017 without any restrictions. The weighted mean difference (WMD) was also calculated using random effects model. Results: Eventually, eight good quality studies were included in the present systematic review and meta-analysis. The pooled analysis showed that although adherence to the PD led to reduction of fasting blood glucose (FBG) concentrations, it was no statistically significant (WMD = -0.31, 95% CI: -0.70, 0.07, P = 0.11). Moreover, compared with the control diets, the PD consumption did not significantly affect other glycemic markers such as 2-h post-prandial blood glucose (2h PBG), insulin, homeostasis model assessment for insulin resistance (HOMA-IR), and Hemoglobin A1c (HbA1c). Conclusions: Adherence to the PD had no significant effect on the glycemic markers, but reduction was observed in FBG levels.

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“…During this time, scientific evidence about the health benefits of ancestral diets has also been accumulating. Benefits for treatment of type-2 diabetes [3], [4], [5], [6], [7], [8], cardiovascular disease [4], [9], [10], [11], multiple sclerosis [12], [13], inflammatory bowel disease [14], obesity [15], and all-cause mortality [16] have been documented through human trials.…”

Section: Scientific Evidencementioning

confidence: 99%

Self-experimentation: a Pathway to Ancestral Health Practices

Chambers-Sinclair¹

2017

jevohealth

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Attenuated Low‐Grade Inflammation Following Long‐Term Dietary Intervention in Postmenopausal Women with Obesity

Abstract: A reduction of abdominal obesity in postmenopausal women is linked to specific changes in inflammation-related adipose gene expression.

Cited by 18 publications

References 41 publications

Influence of Paleolithic diet on anthropometric markers in chronic diseases: systematic review and meta-analysis

Influence of Paleolithic diet on anthropometric markers in chronic diseases: systematic review and meta-analysis

Effects of Paleolithic Diet on Glucose Control in Adults: A Systematic Review and Meta-analysis of Controlled Clinical Trials

Self-experimentation: a Pathway to Ancestral Health Practices

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