Atypical esophageal granular cell tumor: Case report

Benchekroun, Zineb; Akammar, Amal; Bennani, Hajar; Haloua, Meriem; Lamrani, Youssef Alaοui; Boubbou, Meriem; Chbani, Leila; Maâroufi, Mustapha; Alami, Badreeddine

doi:10.1016/j.radcr.2021.09.040

Cited by 3 publications

(1 citation statement)

References 13 publications

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“…in 1945. It is associated with a poor prognosis, manifested by a local recurrence rate of 32%–70%, a metastasis rate of 50%–62%, and a mortality rate of 39%–65% ( 2 , 14 – 16 ). The criteria used to discriminate between benign and malignant GCTs have always been controversial given that the clinical course and pathology of GCTs are not completely consistent.…”

Section: Discussionmentioning

confidence: 99%

Malignant granular cell tumor in the thoracic wall: A case report

Gao

Xing²,

Sun³

et al. 2022

Front. Oncol.

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Granulosa cell tumor (GCT) is a rare tumor that originates from neural/Schwann cells. GCTs can occur at any age and at any site in the body. The most common site is the tongue, followed by the mammary gland, upper respiratory tract ( throat and bronchus), and gastrointestinal tract (esophagus, large intestine and perianal area, stomach, small intestine, and bile duct). Malignant GCTs account for less than 1%–2% of all GCTs. Fewer than five GCTs in the thoracic wall have been reported, almost all of these benign. Here, we report a new case of malignant GCT of the thoracic wall, with rib invasion and pleural metastasis, in an Asian male. Microscopic examination revealed round, granular cells with eosinophilic cytoplasm and without prominent atypia. Despite these findings the disease showed rapid clinical progression. In summary, the tumor, although histologically ‘benign’, was clinically ‘malignant’.

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Section: Discussionmentioning

confidence: 99%

Malignant granular cell tumor in the thoracic wall: A case report

Gao

Xing²,

Sun³

et al. 2022

Front. Oncol.

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Role of endoscopic ultrasound and endoscopic resection in the diagnosis and treatment of esophageal granular cell tumors

Fan

Jiao

Zhu

et al. 2022

Scandinavian Journal of Gastroenterology

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A Case of Mediastinal Granular Cell Tumor Diagnosed via Endobronchial Ultrasound-guided Transbronchial Mediastinal Tumor Biopsy

Yamaguchi,

Mukai,

Ishiyama

et al. 2024

Respiratory Endoscopy

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In this report, we present a case of granular cell tumor (GCT) of the mediastinum diagnosed using endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) biopsy. A 60-year-old woman was referred for the evaluation of a superior mediastinal mass (30 × 40 mm) at the level of the aortic arch with abnormal uptake on 18Ffluorodeoxyglucose positron emission tomography-computed tomography. Upper gastrointestinal endoscopy revealed no tumor; however, stricture was found in the upper esophagus, 20 cm from the incisors. Although a transnasal endoscope (GIF-XP290N; outer diameter at the distal end 5.4 mm, Olympus Medical System, Tokyo, Japan) could be advanced beyond the stricture, endoscopic ultrasound-guided fine-needle aspiration could not be conducted because the scope (FUJINON EG530UT2; outer diameter at the distal end 13.9 mm, Fujifilm Co., Tokyo, Japan) could not be advanced beyond the stricture. Thus, the mediastinal mass was biopsied under EBUS-TBNA, and nests of cells with granular eosinophilic cytoplasm were found, in which pathologically and immunohistochemically, GCT was suggested. The case points out that EBUS-TBNA can be useful for GCT diagnosis in the mediastinum, which is challenging to diagnose via gastroscopy.

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Atypical esophageal granular cell tumor: Case report

Cited by 3 publications

References 13 publications

Malignant granular cell tumor in the thoracic wall: A case report

Malignant granular cell tumor in the thoracic wall: A case report

Role of endoscopic ultrasound and endoscopic resection in the diagnosis and treatment of esophageal granular cell tumors

A Case of Mediastinal Granular Cell Tumor Diagnosed via Endobronchial Ultrasound-guided Transbronchial Mediastinal Tumor Biopsy

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