Atypical Inflammatory Histiocytic Tumor of the Cerebellum; A Histological, Immunohistochemical, and Ultrastructural Study

Figarella‐Branger, Dominique; Gambarelli, D.; Perez-Castillo, M.; Régis, Jean; Péragut, Jean-Claude; Pellissier, J. F.

doi:10.1097/00000478-199008000-00010

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Systemic histiocytosis presenting as multiple sclerosis

Smith¹,

Katz²,

Harris³

et al. 1993

Annals of Neurology

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A patient resembling one with progressive multiple sclerosis in clinical presentation and by magnetic resonance imaging was studied in detail. Some features atypical for multiple sclerosis prompted a persistent search for an alternative cause. The diagnosis of a non-Langerhans systemic histiocytosis involving brain and bone was established and showed a partial response to radiation therapy. This patient illustrates the continued importance of a broad approach to the evaluation of possible multiple sclerosis, with particular attention to atypical features.

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