Atypical Magnetic Resonance Imaging Findings in Hepatocellular Carcinoma

Roumanis, Panayota S.; Bhargava, Puneet; Aubin, Golnaz Kimia; Choi, Joon Il; Demirjian, Aram N.; Thayer, David; Lall, Chandana

doi:10.1067/j.cpradiol.2014.03.002

Cited by 6 publications

(12 citation statements)

References 32 publications

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“…Hypervascular nodules without washout appearance : Well-differentiated and small HCC lesions may show atypical patterns of enhancement with lack of or poor arterial phase enhancement and persistent enhancement in the venous and delayed phases ( Figures 7 ). 38 , 39 , Differential diagnoses are benign hypervascular lesions ( e.g ., hemangioma, focal nodular hyperplasia, and adenomas) and hypervascular metastasis.…”

Section: Imaging Features On Mrimentioning

confidence: 99%

“…Hypovascular nodules : Only about 10% of HCC are hypovascular 38 and the diagnosis can be challenging. However, in a patient with high risk to develop HCC, hypovascular nodules are suspicious.…”

Section: Imaging Features On Mrimentioning

confidence: 99%

“…Usually, these vascular disorders are peripheral, wedge-shaped lesions, isointense to surrounding parenchyma on pre-contrast images and do not present restricted diffusion or displace internal vasculature. 36 , 37 , 38 ,…”

Section: Differential Diagnosismentioning

confidence: 99%

“…However, unlike HCC, it is usually associated with atrophy and capsular retraction of the affected segment, as well as delayed contrast enhancement. 36 , 37 , 38 ,…”

Section: Differential Diagnosismentioning

confidence: 99%

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State of the art in magnetic resonance imaging of hepatocellular carcinoma

Horvat

Monti

Oliveira

et al. 2018

Radiology and Oncology

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BackgroundLiver cancer is the sixth most common cancer worldwide and the second leading cause of cancer mortality. Chronic liver disease caused by viral infection, alcohol abuse, or other factors can lead to cirrhosis. Cirrhosis is the most important clinical risk factor for hepatocellular carcinoma (HCC) whereby the normal hepatic architecture is replaced by fibrous septa and a spectrum of nodules ranging from benign regenerative nodules to HCC, each one of them with different imaging features.ConclusionsFurthermore, advanced techniques including the quantification of hepatic and intralesional fat and iron, magnetic resonance elastography, radiomics, radiogenomics, and positron emission tomography (PET)-MRI are highly promising for the extraction of new imaging biomarkers that reflect the tumor microenvironment and, in the future, may add decision-making value in the management of patients with HCC.

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Section: Imaging Features On Mrimentioning

confidence: 99%

Section: Imaging Features On Mrimentioning

confidence: 99%

Section: Differential Diagnosismentioning

confidence: 99%

“…However, unlike HCC, it is usually associated with atrophy and capsular retraction of the affected segment, as well as delayed contrast enhancement. 36 , 37 , 38 ,…”

Section: Differential Diagnosismentioning

confidence: 99%

See 2 more Smart Citations

State of the art in magnetic resonance imaging of hepatocellular carcinoma

Horvat

Monti

Oliveira

et al. 2018

Radiology and Oncology

View full text Add to dashboard Cite

show abstract

“…One study showed that this type of tumor accounts for 0.24-3.0% of all cases of hepatocellular carcinoma in Japan (11) . It has an atypical presentation, manifesting as an extra-hepatic mass in imaging studies, simulating another type of primary tumor (12) . In another study, there is a report of seven patients with extrahepatic masses seen on computed tomography, all simulating tumors of primary extrahepatic origin, in which the diagnosis of exophytic hepatocarcinoma was established only after percutaneous biopsy, surgical resection, or necropsy (13) .…”

mentioning

confidence: 99%