Atypical presentation of Takayasu aortitis and myocarditis contributing to sudden death in a young Canadian first nations adult

Ferreira, Elizabeth O.; MacDonald, Jennifer; Jassal, Davinder S.; D, Rhee

doi:10.1016/j.carpath.2021.107347

Cited by 2 publications

(1 citation statement)

References 11 publications

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“…51 Other inflammatory diseases such as Behcet disease and Takayasu arteritis can involve the aortic valve and central fibrous body, with the associated fibrosis causing AV block. 58,59 In some cases of aortitis with associated fibrosis and AV block, the specific etiology of the inflammation is unknown but is likely an autoimmune disease. 58,60 Piriou et al 61 have described complete AV block in a patient with Still's disease.…”

Section: Autoimmune Diseasementioning

confidence: 99%

Lesions of the Cardiac Conduction System and Sudden Death

Cohle,

Wygant

2023

Am J Forensic Med Pathol

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When a young previously healthy person dies suddenly, occasionally, the scene is noncontributory and the autopsy and drug screen are negative. In such cases, additional studies, including genetic assessment and cardiac conduction system examination, should be performed. We performed a literature search and reviewed our own material to identify possible or definite conduction system anomalies that may cause death. We identified intrinsic conduction system disease including cystic tumor of the atrioventricular node, atrioventricular node (cystic tumor of the AV node), and fibromuscular dysplasia of the atrioventricular node artery to be likely causes of death. Extrinsic causes, in which a generalized disease affects the conduction system, include tumors, autoimmune disease, infiltrative disorders, and others, are a second category of diseases that can affect the conduction system and cause atrioventricular block and sudden death.

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