Atypical Tuberous Myxedema Jadassohn-Dössekker

Abstract

A 48-year-old male patient with atypical tuberous myxedema Jadassohn-Dössekker, characterized by nodules on both upper legs with mucin deposits, is described. Atypical tuberous myxedema Jadassohn-Dössekker can be classified together with lichen myxedematosus and scleromyxedema Arndt-Gottron as normothyrotic myxodermia. It can be distinguished from lichen myxedematosus only by the size of the lesions. The pathogenesis is unknown.

Nodular Cutaneous Mucinosis – An Unusual Multiple Type of Euthyreotic Focal Mucinosis

“…Lichen myxedematosus variants, such as discrete papular mucinosis or the form with urticarial plaques and nodules [3,4], were thought to be unlikely as the clinical aspect was somewhat different and the histopathological cpidermotropism typical of lichenoid diseases was absent in the examined lesions. Under the diagnosis 'atypical tuberous myx edema Jadassohn-Dossekker'2 cases with multiple tumors, lacking dif fuse swelling of the skin and largely without papular efflorescences were reported [5,6). Like our patient, one of these showed no abnor mal laboratory findings or peculiarities of internal organs [6], How ever.…”

“…Under the diagnosis 'atypical tuberous myx edema Jadassohn-Dossekker'2 cases with multiple tumors, lacking dif fuse swelling of the skin and largely without papular efflorescences were reported [5,6). Like our patient, one of these showed no abnor mal laboratory findings or peculiarities of internal organs [6], How ever. our case differs profoundly from the disease originally described by Dossekker [7], The term 'tuberous myxedema' has incorrectly been used also for cases of lichen myxedematosus, scleromyxedema and probably for localized special forms of normothyreotic mucinoses, to which our case seems to belong.…”

Nodular-Type Lichen Myxedematosus: A Case Report

“…Only three previous cases [4, 5] characterized by nodular-type LM have been reported, including one from Japan. The mean onset age of the four reported patients with nodular-type LM, including our case, was 30.5 years (range 18–48 years), which suggests that this subtype appears at a younger age compared to discrete LM and acral persistent papular mucinosis.…”

Nodular Lichen Myxedematosus During Childhood: A Case Report

“…Nodular lichen myxedematosus (LM) is a rare disease first reported in 1980 by Suter et al . It is a subtype of localized LM with papular or nodular and plaque eruptions, without monoclonal gammopathy and thyroid disease.…”