Au nanoparticles @metal organic framework/polythionine loaded with molecularly imprinted polymer sensor: Preparation, characterization, and electrochemical detection of tyrosine

Chen, Bangjie; Zhang, Yunsong; Li, Lin; Chen, Hui; Zhao, Maojun

doi:10.1016/j.jelechem.2020.114052

Cited by 56 publications

(54 citation statements)

References 41 publications

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“…The lowest LOD and LOQ values were achieved for the PPy/FeCN-SPCE sensor. The results obtained with the sensors developed in this study are comparable with those obtained with other sensors used for the electrochemical detection of L-Tyr reported in the literature, as presented in Table 6 , where some sensors even had lower values of LODs [ 56 , 57 , 58 , 59 , 60 , 61 , 62 , 63 , 64 , 65 ]. However, the sensors developed in this study have a series of advantages.…”

Section: Resultssupporting

confidence: 89%

Development of Polypyrrole Modified Screen-Printed Carbon Electrode Based Sensors for Determination of L-Tyrosine in Pharmaceutical Products

Dinu

Apetrei

2021

IJMS

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Good health, of vital importance in order to carry out our daily routine, consists of both physical and mental health. Tyrosine (Tyr) deficiency as well as its excess are issues that can affect mental health and can generate disorders such as depression, anxiety, or stress. Tyr is the amino acid (AA) responsible for maintaining good mental health, and for this reason, the present research presents the development of new electrochemical sensors modified with polypyrrole (PPy) doped with different doping agents such as potassium hexacyanoferrate (II) (FeCN), sodium nitroprusside (NP), and sodium dodecyl sulfate (SDS) for a selective and sensitive detection of Tyr. The development of the sensors was carried out by chronoamperometry (CA) and the electrochemical characterization was carried out by cyclic voltammetry (CV). The detection limits (LOD) obtained with each modified sensor were 8.2 × 10−8 M in the case of PPy /FeCN-SPCE, 4.3 × 10−7 M in the case of PPy/NP-SPCE, and of 3.51 × 10−7 M in the case of PPy/SDS-SPCE, thus demonstrating a good sensitivity of these sensors detecting L-Tyr. The validation of sensors was carried out through quantification of L-Tyr from three pharmaceutical products by the standard addition method with recoveries in the range 99.92–103.97%. Thus, the sensors present adequate selectivity and can be used in the pharmaceutical and medical fields.

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Section: Resultssupporting

confidence: 89%

Development of Polypyrrole Modified Screen-Printed Carbon Electrode Based Sensors for Determination of L-Tyrosine in Pharmaceutical Products

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Apetrei

2021

IJMS

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“…Despite the many recent advances in disposable and wearable sensing technologies for POCT, current systems are primarily focused on a limited number of metabolites, and few low-cost, flexible, and disposable sensors are available for Tyr POCT [1,2,33]. Most of the current approaches use complex or time-consuming fabrication processes that require sophisticated instrumentation, or solid electrodes, such as glassy carbon electrodes (GCEs), carbon paste electrodes (CPEs) or graphite pencil electrodes, etc., that are not suitable for single-use disposable systems (Table 1) [1,2,26,[33][34][35][36][37][38]. As an alternative, disposable screen-printed electrodes (SPEs) offer fast, affordable, and widespread testing at the point of care, without the need for skilled analysts or complicated measuring equipment [39][40][41].…”

Section: Introductionmentioning

confidence: 99%

Disposable Electrochemical Sensor Using Graphene Oxide–Chitosan Modified Carbon-Based Electrodes for the Detection of Tyrosine

2021

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“…A carbon electrode was molecularly imprinted with a polyaniline/polythionine/gold nanoparticle@zeolitic imidazolate framework-67 composite, and analyzed with a cyclical voltametric method on human serum samples, with satisfactory results: 98.8%. The materials used in the molecular imprinting were selected because of their large surfaces, high porosity, and biocompatibility [47]. In the case of the study carried out by Nihal Ermiş et al, the molecular imprinting was achieved with PPy films on a gold electrode, with excellent results obtained on the human plasma samples used to detect Tyr, demonstrating good reproducibility and repeatability [140].…”

Section: Cps and Mips Involved In Developing Electrochemical Sensors ...mentioning

confidence: 99%

“…The unique physical and chemical properties of CPs and MIPs, such as versatility, adaptability, sensitivity, and adjustable architecture, have led many researchers, including our group, to apply and use these new materials to develop novel chemically modified sensors and biosensors [42]. The polymers that were used in sensors were conductor polymers (CPs)-polypyrrole (PPy) [27,28,43,44], poly(3,4ethylenedioxythiophene) (PEDOT) [45,46], polyalanine (PANI) [47], and polythiophene (PT)-and molecularly imprinted polymers (MIPs) [48,49].…”

Section: Introductionmentioning

confidence: 99%

A Review of Sensors and Biosensors Modified with Conducting Polymers and Molecularly Imprinted Polymers Used in Electrochemical Detection of Amino Acids: Phenylalanine, Tyrosine, and Tryptophan

Dinu

Apetrei

2022

IJMS

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Recently, the studies on developing sensors and biosensors—with an obvious interdisciplinary character—have drawn the attention of many researchers specializing in various fundamental, but also complex domains such as chemistry, biochemistry, physics, biophysics, biology, bio-pharma-medicine, and bioengineering. Along these lines, the present paper is structured into three parts, and is aimed at synthesizing the most relevant studies on the construction and functioning of versatile devices, of electrochemical sensors and biosensors, respectively. The first part presents examples of the most representative scientific research focusing on the role and the importance of the phenylalanine, tyrosine, and tryptophan amino acids, selected depending on their chemical structure and their impact on the central nervous system. The second part is dedicated to presenting and exemplifying conductor polymers and molecularly imprinted polymers used as sensitive materials in achieving electrochemical sensors and biosensors. The last part of the review analyzes the sensors and biosensors developed so far to detect amino acids with the aid of conductor polymers and molecularly imprinted polymers from the point of view of the performances obtained, with emphasis on the detection methods, on the electrochemical reactions that take place upon detection, and on the electroanalytical performances. The present study was carried out with a view to highlighting, for the benefit of specialists in medicine and pharmacy, the possibility of achieving and purchasing efficient devices that might be used in the quality control of medicines, as well as in studying and monitoring diseases associated with these amino acids.

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Au nanoparticles @metal organic framework/polythionine loaded with molecularly imprinted polymer sensor: Preparation, characterization, and electrochemical detection of tyrosine

Cited by 56 publications

References 41 publications

Development of Polypyrrole Modified Screen-Printed Carbon Electrode Based Sensors for Determination of L-Tyrosine in Pharmaceutical Products

Development of Polypyrrole Modified Screen-Printed Carbon Electrode Based Sensors for Determination of L-Tyrosine in Pharmaceutical Products

Disposable Electrochemical Sensor Using Graphene Oxide–Chitosan Modified Carbon-Based Electrodes for the Detection of Tyrosine

A Review of Sensors and Biosensors Modified with Conducting Polymers and Molecularly Imprinted Polymers Used in Electrochemical Detection of Amino Acids: Phenylalanine, Tyrosine, and Tryptophan

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