Auditory Research

McCormick, James G.; Nuttall, Alfred L.

doi:10.1016/b978-0-12-730050-4.50024-7

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The Ear1

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2015

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Cited by 3 publications

(1 citation statement)

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“…The large, accessible guinea pig ear is used for several types of auditory studies (McCormick and Nuttall, 1976). The Preyer or pinna reflex, which involves a cocking of the pinnae in response to a sharp sound, may be used in otologic studies as a measurement of hearing function.…”

Section: The Earmentioning

confidence: 99%

Biology and Diseases of Guinea Pigs

Shomer

Holcombe

Harkness

2015

Laboratory Animal Medicine

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Section: The Earmentioning

confidence: 99%

Biology and Diseases of Guinea Pigs

Shomer

Holcombe

Harkness

2015

Laboratory Animal Medicine

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Altered glycinergic synaptic activities in guinea pig brain stem auditory nuclei after unilateral cochlear ablation

2000

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Bacterial Cytolysin Perturbs Round Window Membrane Permeability Barrier In Vivo: Possible Cause of Sensorineural Hearing Loss in Acute Otitis Media

Engel¹,

Blatz

Schliebs

et al. 1998

Infect Immun

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The passage of radioiodinated streptolysin-O (SLO) and albumin through the round window membrane (RWM) was studied in vivo. When applied to the middle ear, SLO became quantitatively entrapped in this compartment and no passage to the cochlea occurred. However, flux of radioiodinated albumin through the toxin-damaged RWM was observed. We propose that the passage of noxious macromolecules, such as proteases, from a purulent middle-ear effusion may be facilitated by pore-forming toxins, resulting in cochlear damage and sensorineural hearing loss.

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Auditory Research

Cited by 3 publications

References 162 publications

Biology and Diseases of Guinea Pigs

Biology and Diseases of Guinea Pigs

Altered glycinergic synaptic activities in guinea pig brain stem auditory nuclei after unilateral cochlear ablation

Bacterial Cytolysin Perturbs Round Window Membrane Permeability Barrier In Vivo: Possible Cause of Sensorineural Hearing Loss in Acute Otitis Media

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