Augenmanifestationen bei Churg-Strauss-Syndrom

Atili, A.; Richter, C.; Bahn, Erik; Rustenbeck, Hans-Heino; Schittkowski, Michael

doi:10.1007/s00347-013-2815-0

Cited by 2 publications

(1 citation statement)

References 46 publications

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“…The early phase of Churg-Strauss syndrome is characterized by extravascular eosinophilic tissue infiltration in virtually any organ. However, breast involvement is extremely rare [ 31 , 39 ]. It has been previously reported that masses and mastitis are manifestations of breast compromise [ 38 , 40 ].…”

Section: Discussionmentioning

confidence: 99%

Systemic Granulomatous Diseases Associated with Multiple Palpable Masses That May Involve the Breast: Case Presentation and an Approach to the Differential Diagnosis

Jales

Pereira

Stelini

et al. 2014

Case Reports in Medicine

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Palpable mass is a common complaint presented to the breast surgeon. It is very uncommon for patients to report breast mass associated with palpable masses in other superficial structures. When these masses are related to systemic granulomatous diseases, the diagnosis and initiation of specific therapy can be challenging. The purpose of this paper is to report a case initially assessed by the breast surgeon and ultimately diagnosed as granulomatous variant of T-cell lymphoma, and discuss the main systemic granulomatous diseases associated with palpable masses involving the breast.

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Section: Discussionmentioning

confidence: 99%

Systemic Granulomatous Diseases Associated with Multiple Palpable Masses That May Involve the Breast: Case Presentation and an Approach to the Differential Diagnosis

Jales

Pereira

Stelini

et al. 2014

Case Reports in Medicine

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Глазные Проявления При Системных Васкулитах

Кондратюк¹

2020

Офтальмология. Восточная Европа

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Системный васкулит (СВ) – редкая, угрожающая жизни и зрению патология. Обзор литературы посвящен офтальмопатиям при СВ. Представлены наиболее характерные как симптомы, так и поражения глаз с частотой их выявления при различных СВ. Глазной аппарат поражается чаще при болезни Бехчета, гранулематозе с полиангиитом, артериите Такаясу. Глазные манифестации могут быть первым симптомом ранее не выявленного СВ, позволяющим офтальмологу внести свой вклад в его диагностику. Склерит, кератит, увеит, передняя ишемическая оптическая нейропатия являются наиболее частыми глазными проявлениями; васкулит сетчатки, воспалительная инфильтрация орбитальной ткани – наиболее серьезными, угрожающими зрению манифестациями СВ. Учитывая увеличение лабораторных и инструментальных возможностей выявления офтальмологических маркеров СВ, улучшилась верификация данной патологии. Лечение СВ должно быть комплексным: сочетание местного и системного подходов. Риск ухудшения и потери зрения выше у пациентов, которым труднее вызвать ремиссию, и у пациентов с частыми рецидивами. Прогноз офтальмопатий при СВ зависит от локализации воспаления, типа, тяжести поражения глазных тканей и возможности применения иммунобиологической терапии. Использование анти-В-клеточной терапии или ингибиторов TNF-α в комбинации с глюкокортикостероидами улучшает прогноз при лечении СВ. Совместная работа офтальмологов и ревматологов детерминирует успех диагностики и лечения пациентов с СВ. Systemic vasculitis (SV) is a rare, life- and eye- threatening pathology. A review of the literature is devoted to ophthalmopathies during SV. The most characteristic symptoms and eye lesions are presented with the frequency of their detection in various SV. Most often, the ocular apparatus is affected by Behcet’s disease, granulomatosis with polyangiitis, Takayasu arteritis. Eye manifestations may be the first symptom of previously undetected SV, allowing the ophthalmologist to contribute to its diagnosis. Scleritis, keratitis, uveitis, anterior ischemic optic neuropathy are the most common ocular manifestations; retinal vasculitis, inflammatory orbital tissue infiltration are the most serious manifestations of SV that threaten vision. Considering the increase in laboratory and instrumental possibilities for identifying ophthalmic markers of SV, verification of this pathology has improved. Treatment of SV should be comprehensive: a combination of local and systemic approaches. The risk of deterioration and loss of vision is higher in patients who are more difficult to cause remission and with a large number of disease recurrences. The prognosis of ocular manifestations of SV depends on the localization of inflammation, the type, and severity of lesion to the eye tissues and the possibility of using immunobiological therapy. The use of anti-B cell therapy or TNF-α inhibitors in combination with glucocorticosteroids significantly improved the prognosis for SV treatment. The collaborative work of ophthalmologists and rheumatologists determines the success of the diagnosis and treatment of patients with SV.

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Augenmanifestationen bei Churg-Strauss-Syndrom

Cited by 2 publications

References 46 publications

Systemic Granulomatous Diseases Associated with Multiple Palpable Masses That May Involve the Breast: Case Presentation and an Approach to the Differential Diagnosis

Systemic Granulomatous Diseases Associated with Multiple Palpable Masses That May Involve the Breast: Case Presentation and an Approach to the Differential Diagnosis

Глазные Проявления При Системных Васкулитах

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