Augmentation of atrial contribution to left ventricular inflow with aging as assessed by intracardiac doppler flowmetry

Miyatake, Kunio; Okamoto, Masahiro; Kinoshita, Naokazu; Owa, Mafumi; Nakasone, Izuru; Sakakibara, Hiroshi; Nimura, Yuji

doi:10.1016/0002-9149(84)90035-3

Cited by 385 publications

(104 citation statements)

References 15 publications

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“…Legget et al [23] who examined subjects with asymptomatic aortic stenosis, also found higher early and late transmitral flow velocities in women. However, three earlier reports on healthy subjects [20][21][22] found no significant differences between the genders. Systolic Doppler-derived parameters of aortic flow at rest have been previously shown to be unaffected by gender [10][11][12].…”

Section: Doppler Flow Parametersmentioning

confidence: 64%

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Exercise‐induced aortic flow parameters in early postmenopausal women and middle‐aged men

Pines

Drory

et al. 1998

Journal of Internal Medicine

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Objective. Exercise Doppler echocardiography has been recognised as an accurate method for the assessment of left ventricular function in patients with coronary artery disease. Gender differences in aortic flow parameters during exercise have not been well established. The aims of this study were to compare basal ejection Doppler indexes in healthy early postmenopausal women with those of men, and to assess the effects of both isometric and dynamic exercises on these parameters. Design. Intergroup comparison between early postmenopausal women and middle-aged men Subjects. Fifteen healthy women with a mean age of 55 (SD 5) years and 15 healthy men aged 52 (SD 4) were evaluated.Setting. Women were recruited from a menopause clinic and men from a primary cardiovascular prevention program at a cardiac rehabilitation institute. Interventions. Isometric exercise was performed with a 2-hand bar dynamometer, and dynamic exercise with a supine ergometer. Echo Doppler examination was performed at rest and at peak isometric and dynamic exercise with a pulsed Doppler transducer. Results. Both types of exercise resulted in higher values of hemodynamic parameters in the women, with most figures reaching statistical significance. Most aortic flow parameters during rest and exercise were also significantly higher in the women. Conclusions. The unexpected higher values in hemodynamic and aortic flow parameters in early postmenopausal women as compared with middle aged men may shed light on a peculiar aspect of gender differences in cardiovascular function, perhaps specific to this age group and related to menopausal transition.

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Section: Doppler Flow Parametersmentioning

confidence: 64%

“…Prior studies have examined the influence of gender on Doppler indexes mainly during rest [10,11,[19][20][21][22]. The results of these studies with regard to diastolic filling parameters are conflicting.…”

Section: Doppler Flow Parametersmentioning

confidence: 99%

Exercise‐induced aortic flow parameters in early postmenopausal women and middle‐aged men

Pines

Drory

et al. 1998

Journal of Internal Medicine

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“…Senile persons also have reduced early diastolic LV filling and augmented late diastolic filling (3,4). However, the determinant factors responsible for augmentation of atrial active emptying with aging have not been well established.…”

Section: The Left Atrial (La) Pump Function (Active Emptying) During mentioning

confidence: 99%

“…duced early diastolic LV filling and increased late diastolic filling (3,4 (21- 30 years) (6). On the other hand, Thomas et (8).…”

Section: F I G U R E 4 Ag E P L O T T E D a G A I N S T L E F T A Tmentioning

confidence: 99%

Determinants of Enhanced Left Atrial Active Emptying with Aging: Left Atrial Preload, Contractility or Both?

et al. 2009

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“…Elderly patients frequently had a secondary left ventricular dysfunction that increased dependence on atrial systole to maintain an adequate ventricular filling. 12 To avoid this bias the AEF in the present paper was adjusted for patient age. 11…”

Section: Evaluation Of Atrial Function Using Aefmentioning

confidence: 99%

Doppler sonographic evaluation of left atrial function after cardioversion of atrial fibrillation.

Mattioli

Castelli²,

Sternieri³

et al. 1999

Journal of Ultrasound in Medicine

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Restoration of sinus rhythm is not always followed by immediate return of effective atrial contraction. Left atrial mechanical function can be assessed by Doppler echocardiography; in the present study we measured the atrial ejection force, which is a noninvasive Doppler‐derived parameter that measures the strength of atrial contraction. The aim of the present study was to evaluate the influence of clinical and echocardiographic parameters: duration and cause of atrial fibrillation, different modality of cardioversion, and left atrial size with respect to the delay in the return of effective atrial contraction after cardioversion. Seventy patients were randomly chosen to undergo cardioversion by either direct current shock or intravenously administered procainamide hydrochloride. The 52 patients who had sinus rhythm restored underwent a complete Doppler echocardiographic examination 1 h after the restoration of sinus rhythm and after 1 day, 7 days, and 1 month. The relation between clinical variables and atrial ejection force was tested. Atrial ejection force was greater immediately and 24 h after cardioversion in patients who underwent pharmacologic therapy compared to patients treated with direct current shock (11.3+/‐3 versus 5+/‐2.9 dynes; P<0.001). In both groups atrial ejection force increased over time. The mode of cardioversion was significantly associated with recovery of left atrial mechanical function by day 1 in univariate and multivariate analysis (odds ratio, 0.14; 95% confidence interval, 0.02‐1.2). The other variable associated with the delay in the recovery of atrial function was a dilated left atrium (odds ratio, 0.16; 95% confidence interval, 0.12‐1.6). Atrial ejection force is a noninvasive parameter that can be easily measured after cardioversion and gives accurate information about the recovery of left atrial mechanical function. The recovery of left atrial function was influenced by the mode of cardioversion and left atrial size.

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Augmentation of atrial contribution to left ventricular inflow with aging as assessed by intracardiac doppler flowmetry

Cited by 385 publications

References 15 publications

Exercise‐induced aortic flow parameters in early postmenopausal women and middle‐aged men

Exercise‐induced aortic flow parameters in early postmenopausal women and middle‐aged men

Determinants of Enhanced Left Atrial Active Emptying with Aging: Left Atrial Preload, Contractility or Both?

Doppler sonographic evaluation of left atrial function after cardioversion of atrial fibrillation.

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