Ausência da atividade anti-helmíntica de plantas em frangos de corte naturalmente infectados com Heterakis gallinarum (Schranck,1788) Madsen,1949

Fernandes, Rozeverter Moreno; Rodrigues, Maria de Lurdes de Azevedo; Borba, HH; Fernandes, Maria Zenaide de Lima Chagas Moreno; Amorim, Alziro de

doi:10.1590/s0103-84782004000500050

Cited by 13 publications

(7 citation statements)

References 2 publications

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“…Also, these herbal products are particularly useful in cases of resistance to conventional medications. Among these plants, pomegranate has been used in folk medicine and is known to possess antiparasitic, antibacterial, antifungal, and antiviral activities [31][32][33][34][35][36][37]. It is well documented that the pomegranate peels contain various active ingredients including tannins, flavonoids, alkaloids and organic acids.…”

Section: Discussionmentioning

confidence: 99%

“…Furthermore, pomegranate is a potential antifungal and it is casually used in the treatment of Trichophyton rubrum [30]. Pomegranate exhibits several other pharmacological activities, including anthelmintic effects on various intestinal trematodes, nematodes, and cestodes in addition to its anti-amoebic, antimalarial, and anticoccidial effects [31][32][33][34][35][36][37].…”

Section: Introductionmentioning

confidence: 99%

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Pomegranate Peel Extract Is a Potential Alternative Therapeutic for Giardiasis

et al. 2021

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Giardiasis is a major diarrheal disease affecting approximately 2.5 million children annually in developing countries. Several studies have reported the resistance of Giardia lamblia (G. lamblia) to multiple drugs. Therefore, identifying an effective drug for giardiasis is a necessity. This study examined the antiparasitic effect of Punica granatum (pomegranate) and evaluated its therapeutic efficacy in rats infected with G. lamblia. In vitro study showed high efficacy of pomegranate peel ethanolic extract in killing G. lamblia cysts as demonstrated by eosin vital staining. We showed that treating infected rats with pomegranate extract resulted in a marked reduction in the mean number of G. lamblia cysts and trophozoites in feces and intestine respectively. Interestingly, the number of G. lamblia trophozoites and cysts were significantly lower in the pomegranate extract-treated group compared to the metronidazole-positive control group. Moreover, pomegranate extract treatment significantly induced nitric oxide (NO) and reduced serum IL-6 and TNF-α, compared to infected untreated rats. Histological and scanning electron microscopy (SEM) examination of the jejunum and duodenum of pomegranate extract-treated animals confirmed the antiparasitic effect of the extract, and demonstrated the restoration of villi structure with reduction of villi atrophy, decreased infiltration of lymphocytes, and protection of intestinal cells from apoptotic cell death. In conclusion, our data show that the pomegranate peel extract is effective in controlling G. lamblia infections, which suggests that it could be a viable treatment option for giardiasis.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Pomegranate Peel Extract Is a Potential Alternative Therapeutic for Giardiasis

et al. 2021

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“…Pomegranate phytoconstituents that have been identified were gallotannins, ellagitannins, anthocyanins, gallagyl esters, hydroxybenzoic acids, hydroxycinnamic acids, and dihydroflavonols [16,17]. These compounds have been shown to provide antinematodal activity [18][19][20][21].…”

Section: Discussionmentioning

confidence: 99%

Decoction of Pomegranate (Punica Granatum L.) Peel as an Anthelmintic Against Taenia Saginata

Saptarini

Mustarichie

2021

Int J App Pharm

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Objective: The purpose of this study was to investigate the anthelmintic activity of pomegranate (Punica granatum L.) peel decoction against Taenia saginata. Methods: The in vitro assay was conducted by observing the motility of T. saginata, which is isolated from cattle’s gastrointestinal tract, in various concentrations of pomegranate peel decoction with albendazole as a positive control. Results: The results showed that the anthelmintic activity was dependent on decoction concentration and the duration of contact between decoction and nematode. Decoction at moderate concentration causes paralysis, while high concentration causes death. The 75% and 100% pomegranate peel decoction started to cause death at 240 min and 150 min after contact with T. saginata. Conclusion: It was concluded that pomegranate peel decoction has anthelmintic activity.

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“…Researchers found positive results of using plants in the control of helminthes, enabling to decrease in the parasite load in extensive poultry, obtaining high quality products with lower costs and increasing the poultry producer profitability (Fernandes, Rodrigues, Borba, Fernandes & Amorim, 2004).…”

Section: Introductionmentioning

confidence: 99%

Banana leaf in the diet of laying hens in cage free system

Silva

Lima

Valentim

et al. 2019

Acta Sci. Anim. Sci.

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The aim of this research was evaluate the productive performance, egg quality and the endoparasites presence on Carijo laying hens in Cage Free system, fed with two experimental diets, one of them supplemented with fresh banana leaf in natura. Were used 196 laying hens with twenty-four weeks of age, distributed in a completely randomized design with 14 boxes, two experimental diets and seven replicates, by treatment with fourteen birds per experimental unit. The variables analyzed were: feed intake; egg production; egg mass: feed conversion per egg mass; feed conversion per dozen eggs; egg weight; albumen weight; yolk weight; shell weight; yolk percentage; albumen percentage shell percentage; yolk pigmentation and the presence of endoparasites. No influence (p > 0.05) were found, for performance and egg production, in Carijo laying hens fed supplemented with banana leaf in natura. For the treatment with inclusion of banana leaf, yolk pigmentation were superior (p < 0.05) when compared to control diet, producing eggs with more yolks orange color. In respect to endoparasite analysis, there was significant effect (p < 0.05) in the percentage of infections present in excretas. Among the treatments evaluated, the one with banana leaf supplementation reduced in 26.54% the endoparasites presence. The inclusion of banana leaf in the diet of Carijo laying hens does not affect performance and eggs quality and decreases the amount of endoparasites of the genus Strogyloides spp.

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Ausência da atividade anti-helmíntica de plantas em frangos de corte naturalmente infectados com Heterakis gallinarum (Schranck,1788) Madsen,1949

Cited by 13 publications

References 2 publications

Pomegranate Peel Extract Is a Potential Alternative Therapeutic for Giardiasis

Pomegranate Peel Extract Is a Potential Alternative Therapeutic for Giardiasis

Decoction of Pomegranate (Punica Granatum L.) Peel as an Anthelmintic Against Taenia Saginata

Banana leaf in the diet of laying hens in cage free system

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