International Islamic University Malaysia (IIUM) has been contributing to the holistic development of human capital through Islamization of human knowledge. It has also been developing young leaders by inculcating the values and resilience needed to survive as good leaders in the 21st century. This study aims to investigate the levels of perceptions and practices of student leaders’ leadership competencies (LCSL), Islamic Spiritual Intelligence (ISI), Emotional Intelligence (EI), and Islamization of Human Knowledge (IOHK) at IIUM. The current study employs a quantitative cross-sectional survey with a stratified random sampling technique. The data were collected using a self-administered questionnaire, distributed to 372 student leaders in the year 2018/2019. The results from the descriptive analysis revealed that student leaders’ practices and perceptions of IOHK (78%), EI (78%), ISI (91%), and LCSL (79%) exceeded 50%. The results of this study may contribute to the previous models of leadership competencies, such as Islamic Spiritual Intelligence by Jumahat et al., Emotional Intelligence by Goleman, Man of Sound Reasoning of Islamization of Human Knowledge by Hassan, Student Leadership Competencies by Seemiller, and Integrative Global Leadership to Develop Young Leaders by Park et al.