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Kessel, Line; Tendal, Britta; Jørgensen, Karsten Juhl; Erngaard, Ditte; Flesner, Per; Andresen, Jens; Hjortdal, Jesper

doi:10.1016/j.ophtha.2014.08.004

Cited by 4 publications

(3 citation statements)

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“…Development of novel anti-cancer drugs and therapies is always the basic mission for all medicinal chemists. Among the important natural organic compounds occurring in the animals, plants and fungi, steroids have been reported to possess great therapeutic value as antitumor, 1,2 anti-inflammatory, 3,4 and immunostimulant agents. 5 The natural steroidal skeleton has been therefore developed as original anticancer drug candidates, for example, the notable of Withaferin A 6,7 and oxysterols.…”

mentioning

confidence: 99%

Synthesis and cytotoxic activities of 2-substituted (25R)-spirostan-1,4,6-triene-3-ones via ring-opening/elimination and ‘click’ strategy

Yang

Huang

et al. 2015

Bioorganic & Medicinal Chemistry Letters

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mentioning

confidence: 99%

Synthesis and cytotoxic activities of 2-substituted (25R)-spirostan-1,4,6-triene-3-ones via ring-opening/elimination and ‘click’ strategy

Yang

Huang

et al. 2015

Bioorganic & Medicinal Chemistry Letters

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“…4 Few studies also showed that after pterygium excision, the residual corneal astigmatism can be controlled by limbal relaxing incisions, femtosecond laser-assisted astigmatic keratotomy or toric IOL implantation during cataract surgery. 23,24…”

Section: Discussionmentioning

confidence: 99%

Evaluation of changes in the keratometric values after pterygium excision with conjunctival autografting in different grades of pterygium

Damle¹,

Laad

Agarwal³

2021

IJCEO

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To study the changes in keratometric values after pterygium excision with conjunctival autograft in different grades of pterygium. A retrospective, comparative study was done on 75 patients of various grades of pterygium who underwent excision surgery with conjunctival autograft. Preoperative and postoperative details of all the patients on 1, 7 and 30 day were taken into account including detailed ocular examination, best-corrected visual acuity, slit-lamp biomicroscopic examination, keratometric details and posterior segment examination. Net astigmatism was calculated preoperatively and on post-op examinations. Mean of difference in preoperative and post operative net astigmatism is calculated and compared in different grades of pterygium. Our study showed that there are significant changes in net astigmatism after pterygium excision mainly in grade 3 pterygium. Difference in mean net astigmatism at the end of 1 month from preoperative values was 2.39±0.73 in Group C, 1.45±0.5 in Group B and 0.49±0.24 in group C and this difference is significant. The amount of keratometric astigmatism is proportional to grades of pterygium (size of pterygium) and pterygium excision reduces the induced astigmatism and it varies according to grades.

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“…If one eye gets affected, there is a 50% chance that the other eye will also be affected. ME after eye surgery is generally mild, short-lasting, and responds well to medications like eye drops that treat inflammation [12].…”

Section: Eai Endorsed Transactions On Pervasive Health and Technologymentioning

confidence: 99%

Review on the Role of Macular Edema in Retinopathy, Blindness and Automated Diagnosis Methods

Barman¹,

Deb²,

Hassan³

et al. 2021

EAI Endorsed Trans Perv Health Tech

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INTRODUCTION: Macular edema is not a disease itself, but, a very common condition in most of the retinal diseases, such as diabetic retinopathy, retinal vein occlusion, hypertensive retinopathy, age-related macular edema, etc. and postocular surgery. OBJECTIVES: We have discussed how macular edema plays an important role in blindness in case of various retinal blood vascular diseases and post-ophthalmic surgery. We have analyzed vast state-of-the-art methods for retinal abnormality detection. METHODS: The proposed method uses a semi-automated macula segmentation approach and Local Binary Pattern features to train k-Nearest Neighbor classifier and performs binary classification. RESULTS: We have achieved 80% accuracy and 90% sensitivity in classifying normal and abnormal retina CONCLUSION: We justified the notion that it will be beneficial to have a method that can analyse the macula region and alert if there is any abnormality near that region to prevent vision loss.

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Author reply

Cited by 4 publications

References 1 publication

Synthesis and cytotoxic activities of 2-substituted (25R)-spirostan-1,4,6-triene-3-ones via ring-opening/elimination and ‘click’ strategy

Synthesis and cytotoxic activities of 2-substituted (25R)-spirostan-1,4,6-triene-3-ones via ring-opening/elimination and ‘click’ strategy

Evaluation of changes in the keratometric values after pterygium excision with conjunctival autografting in different grades of pterygium

Review on the Role of Macular Edema in Retinopathy, Blindness and Automated Diagnosis Methods

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