Autofluorescence of metastatic choroidal tumor

The Development of Orange Pigment Overlying Choroidal Metastasis

“…However, proliferated RPE might contribute to this finding, since it has been shown that RPE can undergo transdifferentiation to a CD68-positive immunophenotype [16]. Ishida et al [17] described the finding of confluent hyperautofluorescent areas overlying a completely regressed choroidal metastasis from breast cancer after chemotherapy and irradiation without histopathological demonstration.…”

Case of metastatic pulmonary carcinoma in optic disc diagnosed from results of biopsy performed during vitrectomy surgery

“…Results of IA in a case with an optic disc tumour have not been previously reported. In a case of metastatic choroidal carcinoma, the most common intraocular neoplasm [1], FA shows granular hyper-fluorescence along the margin of the tumor and diffuse hyper-fluorescence in the late phase [18]. Choroidal metastasis imaged with IA blocks fluorescence in the early phase and diffuse hyperfluorescence in the late phase [18,19].…”

Diagnostic approach to choroidal metastases

“…По данным литературы, АФ при хориоидальных метастазах характеризует поверхностные измене-ния, в том числе и по краю опухоли [26,27], и, по мнению T. Ishida, является «инвертированным» паттерном ФАГ [28]. Есть основание полагать, что это характерно только для случаев с относительно длительной историей снижения зрения.…”