Autograft Versus Allograft for Posterior Cruciate Ligament Reconstruction: An Updated Systematic Review and Meta-analysis

Abstract

Patients undergoing primary PCLR with either autograft or allograft can be expected to experience improvement in clinical outcomes. Autograft patients experienced less AP knee laxity postoperatively, although the clinical significance of this is unclear and subjective outcomes improved substantially and to a similar degree in both groups.

Posterior cruciate ligament reconstruction implemented by the Ligament Advanced Reinforcement System over a minimum follow-up of 10 years

“…A retrospective study conducted by Chahla et al [15] in 2017 indicated that the employment of the double-bundle technique for autograft and allograft resulted in an average posterior tibial translation of 2.4 and 4.9 mm. Belk et al [16] noted in a review published in 2017 that the anteroposterior laxities of the studied autograft group and the allograft group were 3.1 mm and 3.8 mm, respectively. A retrospective study conducted by Xu et al [17] in 2014 indicated that both the SSD of autograft and LARS were 3.3 mm.…”

Comparisons of Efficacy between Autograft and Allograft on Defect Repair In Vivo in Normal and Osteoporotic Rats

“…The current knowledge in the use of allograft and autograft is that studies verify different outcomes dependent on location. In the cranioplasties, allograft has been shown to be superior [25]; in anterior crucial ligament (ACL), autograft showed better effect on bone formation [26], whereas in the posterior crucial ligament (PCL), the results are equal between the 2 grafts [27,28]. Hence, when comparing results for clinical implementation, using the correct graft is essential for the correct comparisons.…”

Posterior Cruciate Ligament Repair With Suture Tape Augmentation

“…Multiple techniques have been described in the literature for the operative management of patients with injuries to the PCL. 1 , 2 , 6 , 7 , 8 Historically, primary PCL repair was the preferred option; however, PCL reconstruction procedures are currently the most widely used option.…”

“…Belk et al. 2 published a systematic review and meta-analysis of 5 studies with 132 patients performed to compare PCL reconstruction with allograft versus autograft. They reported improved clinical outcomes in both groups but no differences between the groups.…”

“… 1 It originates on the medial femoral condyle and inserts on the posterior intercondylar area of the tibia. 2 The PCL is composed of 2 bundles, an anterolateral bundle and a posteromedial bundle. 3 PCL injury accounts for up to 20% of injuries to the ligaments around the knee.…”