Autoinfarcted Wandering Spleen and Fatal Pneumococcal Sepsis in an Infant

Breisch, Eric; Krous, Henry F.

doi:10.1007/s10024-004-7082-2

Cited by 5 publications

(2 citation statements)

References 24 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Both traumatic rupture and overwhelming sepsis following vascular compromise with autoinfarction have been reported. 72,73 A rare case of primary splenic ectopic pregnancy with haemorrhage has also been described. 74…”

Section: Miscellaneousmentioning

confidence: 99%

Unexpected death involving the spleen – an overview

2023

View full text Add to dashboard Cite

The spleen is located in the left upper quadrant of the abdominal cavity and has both immunological and haematological functions. A variety of quite different entities may be associated with sudden death due to splenic involvement. These range from simple traumatic disruption of the parenchyma of a normal spleen with marked intra-abdominal haemorrhage, to conditions such as malaria and infectious mononucleosis where splenomegaly predisposes to rupture. Haematological diseases such as malignancies and haemoglobinopathies may causes sudden death due to haemorrhage or red cell sequestration. Asplenia or polysplenia may be associated with significant congenital heart disease. Hyposplenia, both structural and functional, may also result in rapid demise from sometimes unusual bacterial infections. Vascular abnormalities causing death include entities such as splenic artery aneurysms. Thus, deaths from splenic pathology may be due to localised issues or may be part of more generalised disease. For this reason the autopsy in cases of splenic-associated deaths must be comprehensive and include special testing such as microbiological screening and/or haematologic/genetic evaluation.

show abstract

Section: Miscellaneousmentioning

confidence: 99%

Unexpected death involving the spleen – an overview

2023

View full text Add to dashboard Cite

show abstract

“…Much of the human data is in the form of case reports documenting failure of splenotic tissue to protect against septicemia, even at times when there was a large amount of splenosis. Articles involving splenosis and OPSI are summarized in Table 1, [78][79][80][81][82][83][84][85][86] while those involving accessory spleens and OPSI are summarized in Table 2.…”

Section: 67-71mentioning

confidence: 99%