Autologous gastrointestinal reconstructive surgery

Fusaro, Fabio; Hermans, Dominique; Reding, Raymond

doi:10.1097/mot.0b013e3283607a16

Current Opinion in Organ Transplantation

2013

DOI: 10.1097/mot.0b013e3283607a16

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Autologous gastrointestinal reconstructive surgery

Fabio Fusaro

Dominique Hermans

Raymond Reding

Abstract: Autologous intestinal reconstructive procedures are pivotal to achieve enteral autonomy in patients with intestinal failure related to SBS. They should be considered mutually supportive and not antagonistic to intestinal transplantation.

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Cited by 4 publications

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Recent Advances in the Management of Pediatric Intestinal Failure

Chan

2014

Pediatrics & Neonatology

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Intestinal failure is a chronic condition in which the intestinal tract has lost most of its function. Prognosis depends on the severity and underlying etiologies. Although many patients survive under parenteral nutrition support, they often suffer from fatal complications such as progressive cholestasis and frequent sepsis. In addition, to decide the proper time to refer selected patients to bowel transplantation remains difficult. A noninvasive biomarker developed to evaluate functional enterocyte mass and the extent of intestinal adaptation is plasma citrulline level. It is shown that serum citrulline correlates with small bowel length, oral tolerance, and parenteral nutrition dependency. Recent evidence has revealed that the use of fish oil containing lipid emulsions to substitute traditional soybean-based formula may reverse a patient's cholestasis and improve lipid profiles. A new method used to prevent catheter-related bloodstream infection is ethanol lock therapy. With both antimicrobial and fibrinolytic activities, studies have shown that ethanol locks can effectively decrease catheter infection and replacement rate with no known resistance reported. As part of intestinal rehabilitation, auxiliary surgeries such as longitudinal intestinal lengthening and tailoring, serial transverse enteroplasty, and tapering enteroplasty can be beneficial for selected patients before bridging to bowel transplantation. With the introduction of these new medical and surgical modalities, patients with intestinal failure are having better outcomes than in the past.

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Recent Advances in the Management of Pediatric Intestinal Failure

Chan

2014

Pediatrics & Neonatology

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Pediatric Intestinal Rehabilitation and Transplantation Registry: Initial Report from a European Collaborative Registry

et al. 2017

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Intestinal failure

Pirenne¹

2013

Current Opinion in Organ Transplantation

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Autologous gastrointestinal reconstructive surgery

Abstract: Autologous intestinal reconstructive procedures are pivotal to achieve enteral autonomy in patients with intestinal failure related to SBS. They should be considered mutually supportive and not antagonistic to intestinal transplantation.

Cited by 4 publications

References 28 publications

Recent Advances in the Management of Pediatric Intestinal Failure

Recent Advances in the Management of Pediatric Intestinal Failure

Pediatric Intestinal Rehabilitation and Transplantation Registry: Initial Report from a European Collaborative Registry

Intestinal failure

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