Automated Analysis of Pharyngeal Pressure Data Obtained with High-Resolution Manometry

Mielens, Jason D.; Hoffman, Matthew R.; Ciucci, Michelle R.; Jiang, Jack J.; McCulloch, Timothy M.

doi:10.1007/s00455-010-9320-2

Cited by 75 publications

(53 citation statements)

References 18 publications

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“…1A). 6,7,11 Anatomically TB pressure is generated at a similar level with the epiglottic pressure. As tilting of the epiglottis strikes the manometric catheter, the tilting epiglottis changes the peak pressure and the area integral ([1] peak in Fig.…”

Section: Analysis Of High-resolution Manometry Datamentioning

confidence: 99%

“…(A) The individual peaks in the areas of interest. Each peak shows [1] velopharyngeal peak, [2] tongue base (TB) peaks, [3] low pharyngeal peak, [4] upper esophageal sphincter (UES) peak, [5] tilting of epiglottis, [6] pre-UES peak, [7] UES activity time, and [8] Nadir UES duration. The [5] peak shows the epiglottic tilting peak in front of the TB peak.…”

Section: Correlation With Volumementioning

confidence: 99%

“…It also has improved sensitivity, reliability, and accuracy. 6 Though informative with potentially high clinical value, it has yet to be applied routinely to the assessment of dysphagia. HRM has revealed subtle pressure differences not previously detected by conventional manometry successfully.…”

Section: Introductionmentioning

confidence: 99%

“…HRM has revealed subtle pressure differences not previously detected by conventional manometry successfully. [6][7][8][9][10] As HRM measures the pressure generation in pharyngeal structures, the main target structures are the velopharynx (VP), TB, epiglottis, and the UES. 7,11 VP is the region between the soft palate and pharyngeal wall.…”

Section: Introductionmentioning

confidence: 99%

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The Effects of Bolus Volume and Texture on Pharyngeal Pressure Events Using High-resolution Manometry and Its Comparison with Videofluoroscopic Swallowing Study

Ryu

Park

et al. 2016

J Neurogastroenterol Motil

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Background/AimsThe purpose of this study was to develop new parameters of high-resolution manometry (HRM) and to applicate these to quantify the effect of bolus volume and texture on pharyngeal swallowing. MethodsTen healthy subjects prospectively swallowed dry, thin fluid 2 mL, thin fluid 5 mL, thin fluid 10 mL, and drinking twice to compare effects of bolus volume. To compare effect of texture, subjects swallowed thin fluid 5 mL, yogurt 5 mL, and bread twice. A 32-sensor HRM catheter and BioVIEW ANALYSIS software were used for data collection and analysis. HRM data were synchronized with kinematic analysis of videofluoroscopic swallowing study (VFSS) using epiglottis tilting. ResultsLinear correlation analysis for volume showed significant correlation for area of velopharynx, duration of velopharynx, pre-upper esophageal sphincter (UES) maximal pressure, minimal UES pressure, UES activity time, and nadir UES duration. In the correlation with texture, all parameters were not significantly different. The contraction of the velopharynx was faster than laryngeal elevation. The durations of UES relaxation was shorter in the kinematic analysis than HRM. ConclusionsThe bolus volume was shown to have significant effect on pharyngeal pressure and timing, but the texture did not show any effect on pharyngeal swallowing. The parameters of HRM were more sensitive than those of kinematic analysis. As the parameters of HRM are based on precise anatomic structure and the kinematic analysis reflects the actions of multiple anatomic structures, HRM and VFSS should be used according to their purposes.

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Section: Analysis Of High-resolution Manometry Datamentioning

confidence: 99%

Section: Correlation With Volumementioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

The Effects of Bolus Volume and Texture on Pharyngeal Pressure Events Using High-resolution Manometry and Its Comparison with Videofluoroscopic Swallowing Study

Ryu

Park

et al. 2016

J Neurogastroenterol Motil

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“…It also has improved sensitivity, reliability, and accuracy. 2 Although HRIM provides precise pharyngeal pressure information, it has yet to be applied to routine clinical practice as the assessment method for dysphagia. The main reason may be that the test method and result interpretation are not easily applicable and standardized.…”

Section: Introductionmentioning

confidence: 99%

Application and Interpretation of High-resolution Manometry for Pharyngeal Dysphagia

Ryu

Park

Kang

2015

J Neurogastroenterol Motil

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The pharyngeal phase of swallowing is a complex event consisted with subsequent muscular contractions and pressure generation to move a bolus from the mouth to the esophagus. Recently, high-resolution impedance manometry (HRIM) was developed and used for the evaluation of pharyngeal dysphagia. Although HRIM provides precise pharyngeal pressure information, it has yet to be used as part of routine clinical practice for the assessment of dysphagia. The main reasons are thought to be that the test method and result interpretation are not easily applicable and standardized. The anatomical landmarks for HRIM parameters are velopharynx, tongue base, epiglottis, low pharynx, and upper esophageal sphincter. With HRIM, the pressure and timing data could be obtained at a precise anatomical structure. In the present review, we will review how to apply HRIM for the evaluation of pharyngeal dysphagia, including the interpretation of its parameters.

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Artificial neural network classification of pharyngeal high‐resolution manometry with impedance data

et al. 2012

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Purpose To use classification algorithms to classify swallows as safe, penetration, or aspiration based on measurements obtained from pharyngeal high-resolution manometry (HRM) with impedance. Study design Case series evaluating new method of data analysis. Method Multilayer perceptron (MLP), an artificial neural network (ANN), was evaluated for its ability to classify swallows as safe, penetration, or aspiration. Data were collected from 25 disordered subjects swallowing 5 or 10 ml boluses. Following extraction of relevant parameters, a subset of the data was used to train the models and the remaining swallows were then independently classified by the ANN. Results A classification accuracy of 89.4±2.4% was achieved when including all parameters. Including only manometry-related parameters yielded a classification accuracy of 85.0±6.0% while including only impedance-related parameters yielded a classification accuracy of 76.0±4.9%. Receiver operating characteristic (ROC) analysis yielded areas under the curve (AUC) of 0.8912 for safe, 0.8187 for aspiration, and 0.8014 for penetration. Conclusions Classification models show high accuracy in classifying swallows from dysphagic patients as safe or unsafe. HRM-impedance with ANN represents one method which could be used clinically to screen for patients at risk for penetration or aspiration.

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Automated Analysis of Pharyngeal Pressure Data Obtained with High-Resolution Manometry

Cited by 75 publications

References 18 publications

The Effects of Bolus Volume and Texture on Pharyngeal Pressure Events Using High-resolution Manometry and Its Comparison with Videofluoroscopic Swallowing Study

The Effects of Bolus Volume and Texture on Pharyngeal Pressure Events Using High-resolution Manometry and Its Comparison with Videofluoroscopic Swallowing Study

Application and Interpretation of High-resolution Manometry for Pharyngeal Dysphagia

Artificial neural network classification of pharyngeal high‐resolution manometry with impedance data

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