The work titled “Arduino Based Covid Disinfection box” aims to build a disinfection box which will sterilize various day-to-day objects like masks and keys. Outbreaks of the virus are highly contagious and life-threatening. One of the necessary steps in the fight against the outbreak of the epidemic and victory over the global pandemic is the disinfection of infected surfaces. Keeping public places safe and clean can be quite challenging, especially if other people are in frequent contact with each other. Common areas and high-contact surfaces are manually disinfected using the hand-held disinfectant. Manual disinfection exposes a cleaner to a contaminated surface by increasing the risk of infection. The use of disinfection box reduces the risk of infection, and overcomes the costs associated with manual cleaning agents. Excessive use of the disinfectant can cause serious health problems. This pandemic forced us to develop and build secure disinfection equipment for UVC disinfection for public spaces. UVC Rays can easily be skipped during manual cleaning and are not harmful to human skin and eyes. The disinfection box provides an effective and efficient solution for disinfecting high-risk and contact surfaces without human intervention.