Automated flow-injection pseudotitration of strong and weak acids, ascorbic acid and calcium, and catalytic pseudotitrations of aminopolycarboxylic acids by use of a microcomputer-controlled analyser

Kinetic determinations and some kinetic aspects of analytical chemistry

“…A very comprehensive monograph entitled "Computers in Analytical Chemistry" has been written by Barker (304) and an excellent technical article entitled "Laboratory Computer Networks" has been published by Borman (305). An automated flow-injection pseudotitration system using a microcomputer-controlled analyzer has been designed by Koupparis et al (306) and a computerized analyzing system for chemiluminescence has been reported by Hayashi and Yuki (307). A correction for a previous paper on computer-assisted optimization for FIA has appeared (308).…”

Kinetic determinations and some kinetic aspects of analytical chemistry

“…A determination of aminopolycarboxylic acids (EDTA, EGTA, DCTA, and DTPA) with Mn(II) as catalytic titrant and the periodate/diethylaniline indicator system was developed to demonstrate the usefulness of flow-injection "pseudotitrations" in catalytic end-point indication (125). A completely automated spectrophotometric system was used; the authors claim that the peak width in time units is simpler and more precise than graphical end-point location and illustrates the kinetic view of flow-injection "pseudotitrations".…”

Peak width and reagent dispersion in flow injection analysis

“…There is thus no reason to limit the concentration of the injected material to values greater than the concentration of the reagent in the carrier stream as seems to be common practice [14]. The larger the volume injected, the smaller the sampling frequency and so speed of analysis is a trade-off for decreasing the C':n/C!…”

“…Thus five orders of magnitude change in concentration can be accommodated on one calibration graph without the base-width becoming impractically large. As time measurements may be made, with fairly simple data logging equipment, to the nearest 0.01 s [14] and precisions of well under 1% RSD may be obtained, it should be possible to distinguish between small relative differences in concentration. At high concentrations of analyte, this may provide a satisfactory measurement of the analyte concentration or, if not, it will give the dilution factor required to bring the concentration onto a more accurate restricted range calibration.…”