2012
DOI: 10.1371/journal.pone.0032352
|View full text |Cite
|
Sign up to set email alerts
|

Automatic Analysis of Composite Physical Signals Using Non-Negative Factorization and Information Criterion

Abstract: In time-resolved spectroscopy, composite signal sequences representing energy transfer in fluorescence materials are measured, and the physical characteristics of the materials are analyzed. Each signal sequence is represented by a sum of non-negative signal components, which are expressed by model functions. For analyzing the physical characteristics of a measured signal sequence, the parameters of the model functions are estimated. Furthermore, in order to quantitatively analyze real measurement data and to … Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
3
1

Citation Types

0
5
0

Year Published

2013
2013
2024
2024

Publication Types

Select...
4
2

Relationship

0
6

Authors

Journals

citations
Cited by 7 publications
(5 citation statements)
references
References 25 publications
0
5
0
Order By: Relevance
“…In general, clustering problems such as the K-means algorithm, EM algorithm, and Self-Organising Map have an issue that the number of clusters should be set manually in advance, as in the case of NMF. For NMF, the rank decision problem has been studied [ 21 – 24 ]. Our framework, however, requires prior knowledge about the data in advance in order to set the rank.…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…In general, clustering problems such as the K-means algorithm, EM algorithm, and Self-Organising Map have an issue that the number of clusters should be set manually in advance, as in the case of NMF. For NMF, the rank decision problem has been studied [ 21 – 24 ]. Our framework, however, requires prior knowledge about the data in advance in order to set the rank.…”
Section: Discussionmentioning
confidence: 99%
“…Thus, NMF has been studied from many perspectives [ 15 , 60 ]. The foundation of NMF has been researched, such as the algorithm [ 16 , 61 63 ], the rank decision problem, including sparseness constraints [ 21 – 24 ], and the initialising problem [ 17 – 19 ]. NMF has been applied to clustering problems [ 64 , 65 ], such as document [ 66 , 67 ], music analysis [ 68 , 69 ], and the community detection problem [ 70 , 71 ].…”
Section: Discussionmentioning
confidence: 99%
“…We can't ensure the repeatability of the results from input data with the true ranks unknown. Previous studies have shown that the rank parameters can be estimated according to the biological experiments or professional knowledge, or based on the statistics of the input data [19]. In our study, we combined the theory of spike firing rate and Takens' embedding theorem to calculate the key parameters.…”
Section: Discussionmentioning
confidence: 99%
“…We next apply the proposed method to the task on factorization of biological signals of protein dynamics in living cells (EGFP) and chemical particle dynamics in an aqueous solution (Rh6G) [17]. Those signals were measured by using fluorescence correlation spectroscopy (FCS) [18].…”
Section: Factorizationmentioning
confidence: 99%