“…Because of its importance in breast cancer diagnosis accurate detection of MCs has become a key research and application task, and a number of approaches have recently been developed, which have been greatly assisting doctors and radiologists in diagnosing breast cancer [1,2]. Among them, focusing on image segmentation and specification of regions of interest (ROI), several methods have been proposed, such as classical image filter and local threshold [3,4], and techniques based on mathematical morphology [5], fractal models [6], optimal filters [7], wavelet analysis and multi-scale analysis [3]. Various classification approaches have also been presented to characterize MCs, such as rule-based systems [8], fuzzy logic systems [9,10], statistical methods based on Markov random fields(MRF) [11], and support vector machines [12].…”