Automatic evaluation of cardiac hypertrophy using cardiothoracic area ratio in chest radiograph images

Hasan, Muhammad Kamil Che; Lee, Seok-Lyong; Kim, Deok‐Hwan; Lim, Myung-Kwan

doi:10.1016/j.cmpb.2011.07.009

Cited by 22 publications

(24 citation statements)

References 14 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Patient’s heart size was determined by 2-D echocardiography and PA CXR. We used CTR as the most common method of describing the heart size (17). …”

Section: Methodsmentioning

confidence: 99%

“…The standard PA CXR (taken by analog calibrated Toshiba system with this criteria: Beam limiting device, model TF-6TL-6, input 1-phase 50/60Hz AC12V, max input power 100VA, max tube voltage 150KV, filtration 1.2 mm) was taken on deep inspiration which was interpreted only by one radiologist and CTR was recorded as shown in Figure 1, which is less than 50 % in normal condition (6, 11, 17). …”

Section: Methodsmentioning

confidence: 99%

See 1 more Smart Citation

Comparison of Radiological Findings of Chest X-Ray With Echocardiography in Determination of the Heart Size

Monfared¹,

Farajollah²,

Sabour³

et al. 2015

Iran Red Crescent Med J

View full text Add to dashboard Cite

Background:Heart size is an important and effective parameter in chest X-ray (CXR) interpretation. Studies indicate that, especially in middle-aged men, increased cardiothoracic ratio (CTR) is associated with ischemic heart disease (IHD) and increased rate of morbidity and mortality. The CXR is the most common imaging examination of the heart.Objectives:A good quality posterior-anterior (PA) chest radiograph is an important indicator of the cardiac size. Nowadays, CXR has given its place to more advanced approaches such as two-dimensional echocardiography. However, CXR is still more accessible and feasible for most of the physicians. This study was designed to compare the findings of CXR and echocardiography in determination of the heart size.Patients and Methods:This cross-sectional study was carried out from 2006 to 2007. A total of 197 patients entered the study. The cases had been undergone PA CXR and 2-D echocardiography maximum within two days.Results:Of participants, 24.9% had cardiomegaly according to the findings of CXR and 50.8% based on echocardiography. There was a statistically significant difference between the mean size of Right Ventricular End Diastolic Diameter in the patients with cardiothoracic ratio < 50% and ≥ 50% (P = 0.002) as well as Left Ventricular End Diastolic Diameter (P = 0.023). Also, a statistically significant difference was seen between echocardiography and CXR findings with regard to determination of the heart size (P = 0.003). Nonetheless, it is noteworthy that sensitivity and specificity of CXR findings in the diagnosis of cardiomegaly were 34%, and 84.5%, respectively.Conclusions:CTR is the most common method of describing the heart size. Increased CTR in CXR is associated with poor prognosis, which is suggestive of importance and necessity of early diagnosis. Although CXR may not have the same diagnostic accuracy as echocardiography, its easy accessibility and high specificity in diagnosis of cardiomegaly is very helpful, which can play an important and a cost-benefit role, particularly in screening the enlarged heart size. Moreover, according to the statistics released by Medical Council of Iran, most of Iranian physicians are general practitioners and a few of them are cardiologist.

show abstract

“…Patient’s heart size was determined by 2-D echocardiography and PA CXR. We used CTR as the most common method of describing the heart size (17). …”

Section: Methodsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Comparison of Radiological Findings of Chest X-Ray With Echocardiography in Determination of the Heart Size

Monfared¹,

Farajollah²,

Sabour³

et al. 2015

Iran Red Crescent Med J

View full text Add to dashboard Cite

show abstract

“…The CTR was assessed by comparing the greatest widths of the heart silhouette and the distance between the thoracic walls at height T8, according to methodology described by Schillaci et al (2009) for Macaca fascicularis and by Hasan et al (2012) in humans. The heart width was measured at the two greatest distances (ML and MR) from the vertical line that divides the limits between the right and left side of the heart, at the point of its greatest diameter.…”

Section: Vertebral Heart Size (Ctr)mentioning

confidence: 99%

“…Cardiac indices such as the Vertebral Heart Size (VHS), already consolidated to estimate the size of the heart silhouette in small animals (Buchanan 2000, Litster & Buchanan 2000 and the cardiothoracic ratio (CTR) widely used in medicine as a prediction of the heart function and life span of cardiac patients (Michiue et al 2010, Hasan et al 2012) are still only rarely used in nonhuman primate Veterinary Medicine.…”

Section: Introductionmentioning

confidence: 99%

Cardiothoracic ratio and vertebral heart size (VHS) to standardize the heart size of the tufted capuchin (Cebus apella Linnaeus, 1758) in computerized radiographic images

et al. 2015

View full text Add to dashboard Cite

RESUMO.-[Índice cardiotorácico e vertebral heart size (VHS) para a padronização do tamanho cardíaco do macaco-prego (Cebus apella Linnaeus, 1758) em imagens radiográficas computadorizadas.] Para a avaliação do VHS e ICT foram utilizadas radiografias toráci-cas computadorizadas de 10 macacos-prego (05 machos e 05 fêmeas) clinicamente saudáveis, oriundos do Centro de Triagem de Animais Silvestres de São Luís-MA-CETAS. Foram tomadas radiografias em projeções laterolaterais e dorsoventrais, para cálculo do Vertebral Heart Scale (VHS) e Índice Cardiotorácico (ICT). O VHS evidenciou valores médios de 9,34±0,32v (machos) e 9,16±0,34v (fê-meas), não ocorrendo diferença estatística entre machos e fêmeas (p>0,05). O ICT evidenciou valores médios de 0,55±0,04 (machos) e de 0,52±0,03 (fêmeas), não sendo verificada diferença estatística entre sexos (p>0,05). Verificou-se correlação positiva entre VHS e ICT (r=0,78). Os diâmetros torácico e cardíaco demonstraram valores médios de 5,70±0,48cm e 3,16±0,40cm nos machos, The VHS and CTR were assessed using computerized thoracic radiographs of ten clinically healthy tufted capuchin monkeys (five males and five females) from the Wild Animal Screening Center in São Luís (Centro de Triagem de Animais Silvestres de São Luís-MA--CETAS). Radiographs were taken in laterolateral and dorsoventral projections to calculate the cardiothoracic ratio (VHS) and vertebral heart size (CTR). The VHS showed mean values of 9.34±0.32v (males) and 9.16±0.34v (females) and there was no statistical difference between males and females (p>0.05). The CTR showed mean values of 0.55±0.04 (males) and 0.52±0.03 (females) and there was no statistical difference between the sexes (p>0.05). There was positive correlation between VHS and CTR (r=0.78). The thoracic and heart diameters showed mean values of 5.70±0.48cm and 2.16±0.40cm in the males, respectively. In the females they measured 5.32±0.39cm and 2.94±0.32cm. There was no statistical difference between the sexes. Our results show that the high correlation found between VHS and CTR permitted the verification with similar clinical precision between the two methods to estimate alterations in the heart silhouette by radiographic examination of tufted capuchin, making it an easy technique to apply that can be considered in the investigation of heart problems for this wild species.

show abstract

“…A total of 64 adult male rats, weighing from 180 to 200 g, were randomly divided into four groups: ten rats in the normal group, ten rats in the sham group, 44 rats in the model group which is established by inducing the cardiac hypertrophy with endothelin and confirmed by electrocardiogram and ultrasonic cardiogram as described previously [6,7]. The rats with cardiac hypertrophy were further divided into two groups: 22 rats in the simple cardiac hypertrophy model group and another 22 rats in the cardiac hypertrophy with H 2 S treatment group.…”

Section: Clinical Datamentioning

confidence: 99%

Hydrogen Sulfide Endothelin-Induced Myocardial Hypertrophy in Rats and the Mechanism Involved

Yang

Liu

Wang

et al. 2014

Cell Biochem Biophys

View full text Add to dashboard Cite

The aim of the study was to evaluate the clinical efficacy of hydrogen sulfide (H2S) treatment on the endothelin-induced cardiac hypertrophy. Sixty-four adult male rats, weighing from 180 to 200 g, were randomly divided into four groups: ten in normal group, ten in sham group, 44 in model group established by inducing the myocardial hypertrophy with endothelin. The myocardial hypertrophy model rats were randomly divided into two groups: 22 in the simple myocardial hypertrophy model group and 22 in the H2S treatment group. Rats in normal group were given 2 ml pure water by gavage per day, those in the sham group and simple cardiac hypertrophy model group were given 2 ml of saline by gavage per day, and rats in the pure cardiac hypertrophy with H2S treatment were given intraperitoneal injections of 2 ml NaHS saline per day for a period of 4 weeks. Left ventricular mass index, myocyte hypertrophy, volume fraction of myocardial interstitial collagen, myocardial hydroxyproline content and other indicators of cardiac hypertrophy were observed after 4 weeks. (1) There were significant differences on the ventricular mass between the treatment group and the cardiac hypertrophy group: The left ventricular mass decreased 21.4 % and the left ventricular mass index decreased 5.97 % (P < 0.05; (2) the smallest cardiomyocytes diameter and cardiomyocytes cross-sectional area decreased 12.5 and 10.8 %, respectively (P < 0.05) in the treatment group compared to the cardiac hypertrophy group; (3) the volume fraction of myocardial interstitial collagen and the myocardial hydroxyproline content decreased 22.3 and 31.3 % in treatment group compared with the cardiac hypertrophy group, respectively (P < 0.05). H2S had a good clinical efficacy in reducing left ventricular mass fraction and myocardial collagen levels, improving myocardial hypertrophy and decrease myocardial fibrosis. It is worthy for further clinical studies.

show abstract

Automatic evaluation of cardiac hypertrophy using cardiothoracic area ratio in chest radiograph images

Cited by 22 publications

References 14 publications

Comparison of Radiological Findings of Chest X-Ray With Echocardiography in Determination of the Heart Size

Comparison of Radiological Findings of Chest X-Ray With Echocardiography in Determination of the Heart Size

Cardiothoracic ratio and vertebral heart size (VHS) to standardize the heart size of the tufted capuchin (Cebus apella Linnaeus, 1758) in computerized radiographic images

Hydrogen Sulfide Endothelin-Induced Myocardial Hypertrophy in Rats and the Mechanism Involved

Contact Info

Product

Resources

About