The purpose of diagnostics is to determine the operability of the pumping units of the pumping station of the machine water lifting at a given time and to identify defects in their components. For this reason, the article presents diagnostic issues for pumping stations No. 1 - No. 6 of the Karshi main canal, designed and commissioned in 1965-1976, where 6 pumping units of the OPV11-260EG type with electric motors of the VDS-375/130-24 type are installed, vertical pumping units, shaft power – 8010 kW, rated power electric motor – 12500 kW, voltage – 10.0 kV, stator current – 825.0 A, maximum permissible temperature of the stator winding – 120 OC, bearing temperature – no more than 70 OC. Diagnostics of the main equipment involves the prompt detection of malfunctions as a result of processing sensor readings of the standard monitoring system, sensor readings are entered manually once a day, and data from monthly and special tests. Technological algorithms of vibration and thermal diagnostics are similar to those developed for vertical pumps installed at thermal power plants, the processes being diagnosed in which are similar to the processes occurring in pumping units of a pumping station. Taking into account the above tasks, algorithms have been developed for diagnosing the main components whose condition affects the performance of the pumping unit: the upper bearing, the upper crosspiece, the stator winding and core, the upper and lower guide bearings, and the electric motor bearing. Possible malfunctions of pumping unit components and ways to eliminate them are given.