Recent theoretical models outline that motor sequence learning involves cognitive control processes that affects stimulus- or plan-based control, although clear contributions from the have not been delineated. Previously, we found that single-session focused attention meditation (FAM) enhanced stimulus-based control through increased top-down activation. In the present experiment, we aimed to understand if single-session FAM effects could be enhanced with short-term FAM training in behavioural reaction time, and neurophysiological indices in the form event-related potentials (ERP). We investigated the N200 component that is closely related to top-down activation, and the error-related negatively (ERN) component that is closely related to error processing for plan development. 29 participants were randomised to one of three conditions reflecting the level of FAM experienced prior to a serial reaction time task (SRTT): 21 sessions of FAM (FAM21, N= 12), a single FAM session (FAM1, N= 9) or no preceding FAM control (Control, N= 8). Continuous 64-channel EEG were recorded during SRTT whereby N200 amplitudes for correct trials, and ERN using mean difference in amplitudes for correct and error trials, were extracted. Component amplitudes, topography and behavioural outcomes were compared using linear mixed effects regression models between groups. Firstly, FAM21 exhibited faster reaction time performances in majority of the learning blocks compared to FAM1 and Control. FAM21 also demonstrated a significantly more pronounced N200 component over all anterior and the central regions during SRTT compared to FAM1 and Control. When N200 amplitudes were modelled against general learning performance, FAM21 also showed the greatest rate of decline over all anterior and the central regions during SRTT compared to FAM1 and Control. No robust differences in the ERN component were found that supported our predictions. The N200 is associated with top-down cognitive control processes, and hence may index stimulus-based learning effects; whilst the ERN is associated with error and updating of an internalised plan that may index plan-based learning effects. Firstly, our results show that after FAM training, top-down activation is increased for better block-on-block RT performances compared to the other groups. More importantly, FAM training facilitates more efficient and dynamic modulation of top-down activation such that at high levels of general learning performance, less top-down control is needed to maintain the performance.