Avaliação da atividade antibacteriana e triagem fitoquímica das flores de Acacia podalyriifolia A. Cunn. ex G. Don Leguminosae-Mimosoideae

Andrade, Cláudia Alexandra de; Peitz, Cristina; Cunico, Miriam Machado; Carvalho, J. L. S.; Abrahão, Wanda Moscalewski; Miguel, Obdúlio Gomes; Miguel, Marílis Dallarmi; Kerber, Vitor A.

doi:10.1590/s0102-695x2005000100004

Cited by 10 publications

(10 citation statements)

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“…The knowledge of the components of a plant from phytochemical selection helps the understanding of its action and its adverse reactions (Andrade et al, 2005;Peitz et al, 2003;Mariz et al, 2006;Carlos et al, 2005). Phytochemical studies of Bauhinia genus confi rm the presence of various isolated and identifi ed compounds, including lactones, fl avonoids, terpenoids, glycolipids, steroid glycosides, steroids, tannins and quinines (Cechinel-Filho et al, 1996, Silva et al, 2000Mendes et al, 2006).…”

Section: Discussionmentioning

confidence: 99%

Determining the genotoxicity of an aqueous infusion of Bauhinia monandra leaves

Macêdo¹,

Sisenando²,

Queiroz³

et al. 2008

Rev. bras. farmacogn.

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Section: Discussionmentioning

confidence: 99%

Determining the genotoxicity of an aqueous infusion of Bauhinia monandra leaves

Macêdo¹,

Sisenando²,

Queiroz³

et al. 2008

Rev. bras. farmacogn.

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“…The material was identified by the botanist José Tadeu Weidlich Motta of the Municipal Botanical Museum of Curitiba and the exsiccate deposited under the number 397798. After drying in the shade, 80 g of seeds were submitted to ethanol extraction, following by liquid-liquid partition with hexane, cloroform and ethyl acetate, using Sohxlet, as per methodology described in previous studies (Andrade et al, 2005(Andrade et al, , 2007Carvalho et al, 2009). After the evaporation of the solvents under reduced pressure and temperature of 40°C, a 0.53 g of hexane fraction, 1.89 g of ethyl acetate fraction, 0.3 g of cloroform, and 0.11 g of ethanol fraction were obtained.…”

Section: Plant Materials and Extraction Proceduresmentioning

confidence: 99%

Determination of antioxidant, radical scavenging activity and total phenolic compounds of Artocarpus heterophyllus (Jackfuit) seeds extracts

Burci¹,

Silva²,

Oliveira³

et al. 2015

J. Med. Plants Res.

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Plants and their parts are a part of life in many brazilian communities, as observed in the jackfruit. The jackfruit seeds are consumed usually as roasted, boiled, steamed, and are eaten as a snack. The present study was carried out to identify the antioxidant, radical scavenging activity and total phenolic compounds of Artocarpus heterophyllus seeds using different screening tests. Total antioxidant activity was determined by ferric thiocyanate method (FTC), which was shortly followed by complexing of fosfomolybdenium method (FSB) determined in sequence with total reductive capability (TRC), hydrogen peroxide scavenging activity (HPS), DPPH free radical scavenging activity, and Total phenolic content (TPC) by Folin-Ciocalteu reagent assay method. The percentage of inhibition linoleic acid peroxidation by CEE (ethanolic extract), HF (hexanic extract), CHLF (chloroform extract) and EAF (ethyl acetate extract) (90.53, 70.23, 68.72 and 92.03%, respectively), in method using prussian blue antioxidant potential for EAF (89,05%) presented antioxidant activity greater than the standard rutin (82.3%). Highest total antioxidant activity was exerted by the ethanolic extract of A. heterophyllus seeds, and lowest by its EAF (188.83%). In evaluating the antioxidant activity by the hidrogen peroxide scavenging activity, it was observed that the CHLF and HF extracts showed scavenging activity above 50% (83.3 and 83.5%, respectively). The EC 50 (free radical scavenger) values of CEE, HF, CHLF and EAF were 76.71, 399.64, 534.83 and 65.51 μg/ml, respectively, and the highest total phenolic content appeared to be present in 125 µg/ml of EAF. The results of all the sources were found to be highly significant. Further investigation for isolation and identification of the phytoconstituents responsible for antioxidant activity is desirable. A. heterophyllus seeds in the regular diets could improve the antioxidant status of human beings.

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“…After drying in the shade, 300 g of flowers of A. podalyriifolia were submitted to ethanol extraction, following by liquid-liquid partition with hexane, dichloromethane and ethyl acetate, using Sohxlet, as per methodology described in previous studies (Andrade et al, 2005;Andrade et al, 2007;Carvalho et al, 2009). After the evaporation of the solvents under reduced pressure and temperature of 40 ºC, a 0.7 g of dichloromethane fraction and 6.3 g of ethyl acetate fraction were obtained.…”

Section: Methodsmentioning

confidence: 99%

“…Several species in the gender Acacia present important medicinal applications (Hagos, Samuelsson, 1988;Chhabra et al, 1990;Nabi et al, 1992;Sekine et al, 1997;Kambizi, Afolayan, 2001;Saleem et al, 2001;Andrade et al, 2003;Meera et al, 2005;Wu et al, 2005) and possess phenolic compounds, for which countless biological activities are described (Kerber, Silva, 1993;Andrade et al, 2003;Meera et al, 2005). However, to date, studies of A.podalyriifolia are scarce (White, 1943;Ballandrin et al, 1978;Anderson, Bell, 1976;Churms et al,1970;Andrade et al, 2003;Andrade et al, 2005;Andrade et al, 2007), motivating research on this species.…”

Section: Introductionmentioning

confidence: 99%

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Antioxidant and antibacterial activity of extracts, fractions and isolated substances from the flowers of Acacia podalyriifolia A. Cunn. ex G. Don

Andrade

Carvalho

Cunico

et al. 2010

Braz. J. Pharm. Sci.

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The extracts and fractions from the flowers of A. podalyriifolia were analyzed previously for antibacterial activity using diffusion in disk, Antioxidant properties were evaluated by determining radical scavenging power (DPPH test) and total phenol content was measured (Folin method). The present study describes the in vitro antibacterial (determining minimum inhibitory concentration) and antioxidant activities (by thiobarbituric acid reactive species -TBARS method) for the ethanol extract, dichloromethane and ethyl acetate fractions and two flavanones (naringenin and 5-β-D-glycosyl-naringenin) isolated from the flowers of Acacia podalyriifolia A. Cunn. ex G. Don. The flavanones naringenin and 5-β-D-glycosylnaringenin had not previously been obtained from this species. The most effective antibacterial activity was observed in the ethyl acetate fraction (MIC=0.25 mg mL -1 against Staphylococcus aureus ATCC 6538, MIC = 0.125 mg mL -1 against Staphylococcus epidermidis ATCC 12229, MIC=0.5 mg mL -1 against Streptococcus pyogenes ATCC 19615, Klebsiella pneumoniae ATCC 13883 and Proteus mirabilis ATCC 43071). The evaluated samples showed antioxidant activity on the TBARS test, especially for ethanol extract (1000 ppm), which was the most active (29.43% ± 0.65) followed by ethyl acetate fraction (1000 ppm, 24.84% ± 1,28), both demonstrating higher activity than that presented by ascorbic acid (1000 ppm, 21.73% ± 1.77), although lower than the BHT (1000 ppm 35.15% ± 3.42), both reference compounds. Naringenin and 5-β-D-glycosyl-naringenin demonstrated antioxidant action, but only naringenin inhibited the growth of gram-positive and gram-negative bacteria.Uniterms: Acacia podalyriifolia/qualitative analysis. Acacia podalyriifolia/phytochemistry. Acacia podalyriifolia/antibacterial activity. Acacia podalyriifolia/antioxidant properties. Flavanones. 5-b-Dglycosyl-naringenin. Naringenin.Os extratos e frações de Acacia podalyriifolia foram analisados previamente para a atividade antibacteriana através da difusão em disco e as propriedades antioxidantes foram verificadas pela determinação da capacidade removedora do radical livre DPPH e pela mensuração do conteúdo de fenólicos totais (Método de Folin). O presente estudo descreve as atividades antibacteriana (determinação da concentração inibitória mínima) e antioxidante (espécies reativas do ácido tiobarbitúrico -teste TBARS) para o extrato etanólico e as frações diclorometano e acetato de etila e para duas flavanonas (naringenina e 5-b-D-glicosilnaringenina) isoladas das flores de Acacia podalyriifolia A. Cunn. ex G. Don. As flavanonas naringenina e 5-b-D-glicosil-naringenina ainda não haviam sido obtidas desta espécie. A atividade antibacteriana mais efetiva foi observada com a fração acetato de etila (CIM=0,25 mg/mL contra Staphylococcus aureus ATCC 6538; CIM=0,125 mg/mL, contra Staphylococcus epidermidis ATCC 12229; CIM=0,5 mg/mL contra Streptococcus pyogenes ATCC 19615, Klebsiella pneumoniae ATCC 13883 e Proteus mirabilis ATCC 43071). As amostras avaliadas demonstraram a...

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Avaliação da atividade antibacteriana e triagem fitoquímica das flores de Acacia podalyriifolia A. Cunn. ex G. Don Leguminosae-Mimosoideae

Cited by 10 publications

References 1 publication

Determining the genotoxicity of an aqueous infusion of Bauhinia monandra leaves

Determining the genotoxicity of an aqueous infusion of Bauhinia monandra leaves

Determination of antioxidant, radical scavenging activity and total phenolic compounds of Artocarpus heterophyllus (Jackfuit) seeds extracts

Antioxidant and antibacterial activity of extracts, fractions and isolated substances from the flowers of Acacia podalyriifolia A. Cunn. ex G. Don

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