Avaliação da atividade antimicrobiana do extrato etanólico bruto da casca da sucupira branca (Pterodon emarginatus Vogel) - Fabaceae

Abstract

RESUMO:Pterodon emarginatus Vogel (Fabaceae) é uma árvore do Cerrado conhecida popularmente como "sucupira branca, faveiro, fava de sucupira e sucupira lisa" e utilizada na medicina popular em preparações anti-reumáticas, antiinflamatórias, analgésicas e antiinfecciosas. Esse trabalho teve por objetivo fazer a triagem fitoquímica do pó e avaliar a atividade antimicrobiana do extrato etanólico bruto das cascas da P. emarginatus contra bactérias Palavras-chave: plantas medicinais, CIM, bactériaABSTRACT: Evaluation of antimicrobial activity of crude ethanol extract from the bark of "sucupira branca" (Pterodon emarginatus Vogel) -Fabaceae. Pterodon emarginatus Vogel (Fabaceae) is a Cerrado tree popularly known as "sucupira branca", "faveiro", "fava de sucupira" and "sucupira lisa" and has been used in folk medicine as antirheumatic, anti-inflammatory, analgesic and anti-infective. The aim of this work was to perform the phytochemical screening of the powder and to evaluate the antimicrobial activity of crude ethanol extract from P. emarginatus barks against Gram-positive bacteria, Gram-negative bacteria and the fungus Candida albicans. The crude ethanol extract was obtained from desiccated and pulverized barks. Its minimum inhibitory concentration (MIC) was determined by using Steers inoculator. The phytochemical tests detected the presence of flavonoids, saponin heterosides, resins and traces of steroids and triterpenoids. Ethanol extract MICs were 0.18 mg mL -1 for the Gram-positive bacteria Rhodococcus equi ATCC 25923, Micrococcus luteus ATCC 9341 and Micrococcus roseus IPTSP/UFG, and for the Gramnegative bacteria Serratia marcescens ATCC 14756 and Pseudomonas aeruginosa ATCC 9027; 0.37 mg mL -1 for Enterobacter cloacae FT 505 LEMC/EPM/UFG; and 0.74 mg mL -1 for the remaining tested bacteria and for the fungus C. albicans. This study opens perspectives for the use of P. emarginatus barks as an antimicrobial drug.

Sucupira as a Potential Plant for Arthritis Treatment and Other Diseases

“…The improvement of the purification and isolation methods using mass and ultraviolet spectrometry and infrared and nuclear magnetic resonance techniques has allowed the elucidation of complex structures in plant materials [ 26 , 27 ]. Phytochemical studies on the genus Pterodon have demonstrated the presence of isoflavones, sesquiterpenes, and diterpenes in its fruit oil [ 1 , 28 – 30 ]; isoflavones and triterpenes in the wood [ 31 , 32 ]; alkaloids, saponins, glycosides, and steroids in the bark of the trees [ 24 , 33 ]; and steroids, sesquiterpenes, isoflavones, and saponins in the leaves [ 34 , 35 ].…”

“…emarginatus bark showed a different outcome since the use of its ethanol extract against Gram-positive and Gram-negative bacteria and against the fungus Candida albicans was effective against Rhodococcus equi , Micrococcus luteus , Micrococcus roseus (MIC: 0.18 mg/mL), Serratia marcescens , Pseudomonas aeruginosa (MIC: 0.37 mg/mL), Enterobacter cloacae , and C . albicans (MIC: 0.74 mg/mL) [ 33 ].…”

A Green Protocol for Microwave-Assisted Extraction of Volatile Oil Terpenes from Pterodon emarginatus Vogel. (Fabaceae)

“…The seed oil and extracts of the bark and stems of P. emarginatus are used in Brazilian folk medicine to treat rheumatism, control diabetes, antimicrobial, anti-inflammatory and analgesic agent [7]. Among others, lupeol, botulin triterpenes, flavonoids, saponosides were identified in stem bark and seed extracts [8,9,10]. …”

Nanoemulsion from essential oil of Pterodon emarginatus (Fabaceae) shows in vitro efficacy against monogeneans of Colossoma macropomum (Pisces: Serrasalmidae)

“…The seeds of P. emarginatus have also been reported to have antimicrobial, anti‐ulcerogenic and leishmanicidal action (Dutra, Braga, Coimbra, Silva, & Barbosa, ). Tea made from the husk of the stalk is used to treat gynaecological infections (Alves et al., ; Bustamante et al., ; Leite de Almeida & Gottlieb, ; Lorenzi, ; Mors, Santos, Monteiro, & Gilbert, ; Santos et al., ). Oil from P. emarginatus has been used as an anti‐inflammatory agent, especially in the form of a microemulsion (Pascoa, Diniz, Florentino, Costa, & Bara, ) and as a nanoemulsion for biological control over the larvae of Aedes aegypti (Oliveira et al., ).…”