Avaliação do estado nutricional de crianças e adolescentes com bronquiolite obliterante pós-infecciosa

Abstract

Objective: To assess the nutritional status of children and adolescents with bronchiolitis obliterans and to analyze associations with clinical and nutritional factors. Methods:The study included 57 patients. Nutritional status was assessed using z scores for weight/age, stature/ age, weight/stature in children, and stature/age and body mass index percentiles in adolescents. Body composition was assessed via tricipital skin folds, subscapular skin folds, and the sum of both plus the muscular circumference of the arm; pulmonary function was also investigated in subjects over 8 years old. Results:The high percentages of malnutrition and risk for malnutrition are noteworthy: 21.7 and 17.5%, respectively. Among children, weight/age and stature/age detected higher percentages of malnutrition (21.6 and 16.2%), while weight/stature underestimated this diagnosis. Among adolescents, body mass index detected a high percentage of malnutrition (25%) and of risk for malnutrition (20%). Body composition analysis detected 51% of patients with low muscle reserves, and the majority of patients had normal fat reserves. Compromised pulmonary function was associated with poor performance at exercise (r = 0.434; p = 0.024). Malnutrition and/or nutritional risk and low muscle reserves were significantly associated with the 6-minute walk test (p = 0.032; p = 0.030). There was no association between spirometry and the nutritional variables (p > 0.05). Conclusion:These results emphasize the need for nutritional intervention, and suggest that, in addition to using weight and height indices for nutritional assessment, it is necessary to combine these with an analysis of body composition, so that a larger number of patients with malnutrition and/or at an increased risk for developing malnutrition may be identified and correctly managed.J Pediatr (Rio J). 2008;84(4):323-330: Bronchiolitis obliterans, nutritional status, body composition, anthropometry, malnutrition, spirometry.

Hypoxemia is an independent predictor of bronchiolitis obliterans following respiratory adenoviral infection in children

“…It is featured by tachypnoea, increased anteroposterior chest diameter, crackles, wheezing, and hypoxaemia for at least 30 days after the initial insult. Luminal obstruction with inflammation, granulation tissue, fibrosis, obliteration of the small airways and bronchiectasis are the pathological characteristics (Li et al 2014 ; Champs et al 2011 ; Xie et al 2014 ; Bosa et al 2008 ; Mosquera et al 2014 ). Due to its poor prognosis and shortage of effective remedy, identification of predictive factors for BO became one of hottest topic in this field.…”

[ARTIGO RETRATADO] Exercício e suas interações com vários aspectos da vida do homem e dos animais

“…They suggest that due to its greater feasibility, the 6-minute walk test could be an alternative where pulmonary function testing is not available. Bosa et al 44 assessed associations of clinical and nutritional factors of 57 children and adolescents with bronchiolitis obliterans. High percentages of malnutrition and risk for malnutrition, such as low muscle reserves, were noted although fat reserves, although fat reserves were normal.…”

Complication of post-infectious bronchiolitis obliterans (Swyer-James syndrome)

“…BO affects mainly male children during the first year of life. [1][2][3] Despite the lack of available epidemiology, there is a high prevalence in countries within the southern hemisphere, such as Argentina, Brazil, Chile and New Zealand. 4,5 There are several etiologies mentioned in the literature, including viral and bacterial infections, but the most frequent cause of BO in children is post-infectious, i.e.…”