SummaryNo-carrier-added 31 Si was produced by 31 P(n,p) 31 Si in the nuclear reactor of the Delft University of Technology. Several methods were investigated to remove the side product 32 P, and the chemical form of 31 Si was investigated. All methods except one gave good results. Anion exchange with Dowex resin gave the best results in activity concentration (3.8 Â 10 6 Bq/ml, with only 3.2 Â 10 3 Bq/ml 32 P as by-product) and specific activity (A s >17 TBq/g). The product is suitable for biological systems.