Axially Ligated Zirconium(IV) Tetraphenylporphyrin: Synthesis, Characterization, and Biological Activity

Abstract

A series of 5,10,15,20-tetraphenylporphinatozirconium(IV) acetylacetonatophenolates containing different phenols as axial ligands [Zr(TPP)(Y)(X)] (TPP = 5,10.15,20-tetraphenyl-21H, 23H-porphine; Y = acac; X = different phenolates) have been synthesized and characterized by various spectrochemical studies. The complexes were also screened for antimicrobial activities. Antifungal activity of some adducts has been carried out against the fungal strain Sclerotium rolfsii. Most of the complexes have shown good antibacterial activity.

Porphyrins as Chelating Agents for Molecular Imaging in Nuclear Medicine

“…The reaction of Zr-acetylacetone with p -methoxy-meso-tetraphenylporphyrin [ 88 ] and meso-tetraphenylporphyrin [ 89 ] in the presence of phenol and its derivatives in chloroform (conducted at 200–220 °C over a salt bath) resulted in the formation of corresponding axially ligated complexes [Zr( p -OCH 3 TPP)(Y)(X)] and [Zr(TPP)(Y)(X)], where Y = acac and X = phenolates. The coordination number of zirconium in both complexes was reported as seven, and due to the large ionic radius of Zr(IV), the metal is out of the plane of the porphyrin ring.…”