Azoospermia factor microdeletion in infertile men with idiopathic severe oligozoospermia or non-obstructive azoospermia

Atia, Tarek; Abbas, Muzaffar; Ahmed, AF

doi:10.1016/j.afju.2015.02.004

Cited by 9 publications

(8 citation statements)

References 26 publications

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“…It was 9.4% among male infertile patients from the United States as reported by Stahl et al ( 2010 ). The data recorded in Turkey and Jordan revealed frequencies as 3.3% (Sargin et al, 2004 ) and 4.93% (Batiha et al, 2018 ), whereas from two other Middle East countries Syria and Saudi Arab reported frequency of 28.4% (Al‐Achkar et al, 2013 ) and 22% (Atia et al, 2015 ), respectively. Among the Asian populations, the study on the Chinese population by Liu et al reported a frequency of 16.9% (Liu et al, 2016 ) in infertile male patients which is consistent with our study.…”

Section: Discussionmentioning

confidence: 97%

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Prevalence of Y chromosome microdeletion in azoospermia factor subregions among infertile men from West Bengal, India

Dutta

Paladhi

Pal

et al. 2021

Molec Gen & Gen Med

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Infertility is a major challenge to reproductive health and the etiology involves both genetic and environmental risk factors. Approximately 15% of couples are infertile across the globe, and the origin of problems is shared almost equally by both the sexes (Poongothai et al., 2009). The problem of male infertility remains unaddressed in Indian society owing to male domination and illogical male chauvinism. Low sperm count is a clinically established cause of infertility among Indian

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Section: Discussionmentioning

confidence: 97%

“…Surprisingly, the cause of male factor infertility in more than half of the cases remains unknown. It could be congenital or acquired and can be categorized grossly on the basis of the poor quality of spermatozoa in the semen and unexplained infertility with normal semen parameters (Atia et al, 2015 ).…”

Section: Introductionmentioning

confidence: 99%

Prevalence of Y chromosome microdeletion in azoospermia factor subregions among infertile men from West Bengal, India

Dutta

Paladhi

Pal

et al. 2021

Molec Gen & Gen Med

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“…Considering that the oldest mean age was in mixed pattern, the mean age of ES + other was high. Fertility in males was related to the number and quality of the spermatozoids; therefore, aging could affect semen volume and influence males fertility ( 15 ). Different studies showed that aging could reduce the fertility in both males and females.…”

Section: Resultsmentioning

confidence: 99%

Testicular Biopsy in Males With Infertility: A Longitudinal Study

2017

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Background & objective: Regarding the importance of histologic examination of testicular biopsy for clinical planning of infertility, the current study was conducted to compare 2 separate histologic examination of testicular biopsy. Also, some cases with known fertility outcome were followed and their histological patterns were also compared with those of the outcome. Methods: The current study was conducted on testicular biopsies of 924 males evaluated for infertility from 1990 to 2013, retrieved from the archive of pathology department of Shahid Beheshti Hospital, Babol, Northern Iran. All slides were reviewed by a pathologist unaware of the original results. Data including age, histological pattern of spermatogenesis (pure and mixed), smoking, and the history of ejaculatory duct obstruction were retrieved from the pathology archive. In some cases, the outcome was also compared with that of the histological pattern. All analyses were executed using SPSS version 22 statistical software. To analyze the data, t test, Chi-square test, one-way ANOVA, and the least significant difference (LSD) test were used. Results and Conclusion: Out of the 924 testicular biopsies, 34 (3.7%) cases had different reports from original reading. LSD analysis indicated Sertoli cell only syndrome (SCO) as the most common histological pattern. There was a significant difference between the mean age of cases with SCO and that of the ones with hypospermatogenesis (HYPO) (P =0.03). Obstruction was higher in pure pattern (P=0.04). The pregnancy rate was higher in the wives of males with obstructive infertility than the ones with non-obstructive infertility. SCO was the most common histological pattern of testicular biopsy during 23 years. Pure patterns were more than mixed patterns, and the mean age was lower in mixed patterns. Also, pure patterns were the most common findings in the cases with obstructive infertility.

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“…Y chromosome microdeletions are often diagnosed worldwide in a variable percentage of infertile men. 16 This study focused on the frequency of AZFa microdeletions in the Y chromosome and defined the types of AZFa microdeletions among infertile Iraqi men.…”

Section: Discussionmentioning

confidence: 99%

Detection of partial and/or complete Y chromosome microdeletions of azoospermia factor a (AZFa) sub‐region in infertile Iraqi patients with azoospermia and severe oligozoospermia

Al-Ouqaili

Al‐Ani

Alaany

et al. 2022

Clinical Laboratory Analysis

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Azoospermia factor microdeletion in infertile men with idiopathic severe oligozoospermia or non-obstructive azoospermia

Cited by 9 publications

References 26 publications

Prevalence of Y chromosome microdeletion in azoospermia factor subregions among infertile men from West Bengal, India

Prevalence of Y chromosome microdeletion in azoospermia factor subregions among infertile men from West Bengal, India

Testicular Biopsy in Males With Infertility: A Longitudinal Study

Detection of partial and/or complete Y chromosome microdeletions of azoospermia factor a (AZFa) sub‐region in infertile Iraqi patients with azoospermia and severe oligozoospermia

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