B‐Cell Neoplasms

Valli, V. E.

doi:10.1002/9780470344545.ch3

Veterinary Comparative Hematopathology 2007

DOI: 10.1002/9780470344545.ch3

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B‐Cell Neoplasms

V. E. Valli¹

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Cited by 10 publications

(1 citation statement)

References 187 publications

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“…In veterinary medicine, plasmablastic lymphoma, a rare variant of aggressive B-cell lymphoma, was reported to be CD20-positive and less often CD79-positive. 23 For all of these reasons, an IgA-producing plasmablastic lymphoma was considered unlikely in this dog.…”

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confidence: 92%

Plasma cell leukemia with plasmablastic morphology in a dog

et al. 2019

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A 5-y-old female Golden Retriever was presented with a 2-wk history of hyporexia, vomiting, diarrhea, lethargy, weight loss, polyuria, and polydipsia. Clinical examination and ultrasonography revealed multiple organ enlargement with gallbladder and kidney nodules suggestive of disseminated neoplasia. Hematologic and biochemical analyses revealed pancytopenia, hypercalcemia, and monoclonal IgA gammopathy suspicious for a plasma cell neoplasm. Bone marrow and blood smear examination revealed neoplastic atypical cells highly suggestive of lymphoid origin. Autopsy confirmed the presence of homogeneous white masses and multifocal pale infiltrates in the spleen, kidney, small intestine, gallbladder, and urinary tract. Histologic features were consistent with a multicentric atypical plasma cell tumor. Tumor cells were negative for CD204, IBA-1, E-cadherin, CD3, CD5, CD79a, CD20, and PAX5, and positive for MUM1, consistent with plasma cell origin. The presence of > 20% of circulating blastic plasma cells was consistent with primary plasma cell leukemia with plasmablastic morphology, a disease rarely described in veterinary medicine.

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confidence: 92%

Plasma cell leukemia with plasmablastic morphology in a dog

et al. 2019

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Proteinuria in canine patients with lymphoma

Bella¹,

Maurella

Cauvin³

et al. 2012

J of Small Animal Practice

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Marginal zone lymphoma in a dog

Burgess

Dickinson

Kerr

et al. 2020

Veterinary Clinical Pathol

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A 13-year-old spayed female, American Cocker Spaniel, was presented to the referring veterinarian for evaluation of a cough and weight loss. Physical examination findings included a heart murmur, generalized lymphadenopathy, and severe dental disease. Thoracic radiographs revealed cardiomegaly with a soft tissue opacity dorsal to the heart (suspected to be an enlarged peri-hilar lymph node). Ethylenediaminetetraacetic acid (EDTA)-anticoagulated blood,

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B‐Cell Neoplasms

Cited by 10 publications

References 187 publications

Plasma cell leukemia with plasmablastic morphology in a dog

Plasma cell leukemia with plasmablastic morphology in a dog

Proteinuria in canine patients with lymphoma

Marginal zone lymphoma in a dog

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