B-glucan immunostilulation against columnaris in a white sturgeon (Acipenser transmontanus) model

Innate immune and chronic heat stress responses in sturgeons: Advances and insights from studies on Russian sturgeons

“…Factors such as the pathogen type (viruses, bacteria, fungi, protozoa, and worms) and localisation (mucosal vs. non-mucosal tissues) determine the type of immunostimulation needed for an effective and beneficial response. Contrasting results were found when -glucan stimulation was used to improve the defence against bacteria ( Flavobacterium columnare [134] ) and fungi ( V. bodryosa [81] ). Although the tools for studying sturgeon immunity are still limited, this is an emerging and promising area of research.…”

“…Furthermore, this validation should be carried out for each Acipenser species, given that the family Acipenseridae spans species that arose millions of years apart, with variable life histories, broad geographical distribution, and distinct responses to stress [49] . Stimulation treatments aimed at enhancing sturgeon defence and/or antioxidative mechanisms have been performed using a variety of products, including yeast cell-wall extracts [12] , -glucans [81] , [134] , recombinant IL-1 [135] , and natural plant derivatives [136] . However, the responses elicited by these treatments remain poorly understood and likely depend on many factors (such as dose, route of administration, and time of treatment).…”

Impact of B-Glucan Against Ehrlich Ascites Carcinoma Induced Renal Toxicity in Mice

“…B-Glucans (BG) are among these polysaccharides, that are found in the structural constituent of the cell walls of various micro-organisms including bacteria, yeast and fungi (Murphy et al, 2020;Rattanachan et al, 2020;Nguyen et al, 2022). BG is a natural product that is universally utilized in cosmetics, foods, and medicine (Gülmen, 2011;Choromanska et al, 2018;Dixon et al, 2022).…”