B-type natriuretic peptide as a marker for sepsis-induced myocardial depression in intensive care patients*

Abstract

These results indicate that plasma BNP concentration represents a reliable marker for identification of patients developing sepsis-induced myocardial depression. In addition, BNP concentration on day 5 may be used as a prognostic marker to identify patients with an elevated risk for an adverse outcome.

Combination of Acute Physiology and Chronic Health Evaluation II score, early lactate area, and N-terminal prohormone of brain natriuretic peptide levels as a predictor of mortality in geriatric patients with septic shock

“…N-terminal prohormone of brain natriuretic peptide has been found to be a useful marker in the diagnosis, management, and prognosis of patients with congestive heart failure. In early stages of septic shock, impaired myocardial function plays an important prognostic role [43]. There is a close inverse relationship between increased plasma NT-proBNP concentrations and depressed left ventricular ejection fraction, and plasma NT-proBNP concentration represents a reliable marker for identification of patients developing sepsis-induced myocardial depression [43].…”

Left ventricular global longitudinal strain is independently associated with mortality in septic shock patients

“…Although the prognostic values of biomarkers in sepsis remain controversial, cTnT [37], BNP [38], and hsCRP [39] have been reported to be prognostic predictors in septic patients. Therefore, we investigated the prognostic value of these biomarkers in our patients and assessed the potential relationships of these biomarkers with GLS.…”

NT-proBNP correlates with the illness scores pneumonia severity index and CURB-65 in patients with pneumonia

“…Brain natri- uretic peptides along with other cardiac markers such as troponin have been found significantly elevated in sepsis and septic shock. 6,7 Few studies coming out in the last few years showed a good prognostic power of BNP to predict severity and prognosis of pneumonia. [8][9][10][11][12] Patients with pneumonia frequently face hypoxemia or respiratory failure which can be just part of the more complex SIRS and which can affect heart function.…”