B-type natriuretic peptide levels predict outcome after neonatal cardiac surgery

Hsu, Jong Hau; Keller, Roberta L.; Chikovani, Omar; Cheng, Henry; Hollander, Seth A.; Karl, Tom R.; Azakie, Anthony; Adatia, Ian; Oishi, Peter; Fineman, Jeffrey R.

doi:10.1016/j.jtcvs.2007.04.017

Cited by 52 publications

(41 citation statements)

References 24 publications

(48 reference statements)

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“…Few studies have reported on the prognostic value of BNP in patients with univentricular heart, most of which had a relatively short follow-up period [26][27][28]. Hsu et al showed that high BNP concentration 12 h after BDCPA procedure predicts a longer hospital stay and a higher risk of unplanned intervention after BDCPA [29].…”

Section: Discussionmentioning

confidence: 99%

B-type natriuretic peptide at the early stage of univentricular circulation reflects inadequate adaptation to volume overload

Inuzuka

Tatebe

Wakiguchi

et al. 2012

International Journal of Cardiology

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Section: Discussionmentioning

confidence: 99%

B-type natriuretic peptide at the early stage of univentricular circulation reflects inadequate adaptation to volume overload

Inuzuka

Tatebe

Wakiguchi

et al. 2012

International Journal of Cardiology

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“…(2007) опре-делили, что у новорожденных повышение BNP в раннем послеоперационном периоде (первые 24 ч после опера-ции) ассоциировалось с увеличением времени искусствен-ной вентиляции легких и вероятности синдрома малого сердечного выброса, внезапной смерти в течение 6 мес. после оперативного вмешательства и трансплантации сер-дца [67]. Группа других исследователей под руководством Shih С.Y.…”

Section: прогностическая роль натрийуретических пептидовunclassified

A clinical importance of natriuretic peptides in pediatric practice

Саперова¹,

Вахлова²

2017

PKiK

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Natriuretic peptides (NUP) are peptide hormones secreted by cardiomyocytes in response to a volume overload of the heart. Emphasis in the article is placed on the history of NUP discovery, their chemical structure and pathophysiological mechanisms of action. The data on determination of NUP reference values in children with cardiac pathologies are analyzed. A NUP clinical significance in early diagnosis of heart failure in children, including those with congenital heart defects is shown. Also considered is NUP dynamics after surgical correction of congenital heart defects. A conclusion is drawn that NUP play an important prognostic role in evaluating early and late postoperative periods and disease outcomes on a whole.Received 11 October 2016. Accepted 22 December 2016.Funding: The study had no sponsorship.Conflict of interest: The authors declare no conflict of interest.Author contributionsAll authors contributed equally at all stages of the research.

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“…Higher BNP values are associated with severity of illness [87], the duration of mechanical ventilation [88], intensive care unit stay [88], the need for inotropic support [89] and low cardiac output syndrome [88]. Cantinotti et al reported, in 162 children who underwent cardiac surgery, that peak BNP was an independent predictor of time to extubation in older children [90].…”

Section: Reviewmentioning

confidence: 99%

Biomarkers in congenital heart disease: do natriuretic peptides hold the key?

Alonso‐Gonzalez

Dimopoulos

2013

Expert Review of Cardiovascular Therapy

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Congenital heart disease is the most common congenital abnormality. The long-term prognosis of these patients has changed significantly over the last half century, thanks to improvements in cardiovascular diagnosis, surgery and postoperative care. However, residual lesions are not uncommon and many of the interventions performed remain palliative rather than reparative, leading to the development of ventricular dysfunction and heart failure. Natriuretic peptides are well-established markers of disease severity and prognosis in patients with heart failure due to noncongenital (acquired) heart disease. However, the role of biomarkers in congenital heart disease is unclear. This review highlights the impact of neurohormonal activation in patients with congenital heart disease, as well as the usefulness of assessing natriuretic peptide levels in specific clinical situations.

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B-type natriuretic peptide levels predict outcome after neonatal cardiac surgery

Abstract: In neonates undergoing cardiac surgery, an increase in B-type natriuretic peptide 24 hours after surgery predicts poor postoperative outcome.

Cited by 52 publications

References 24 publications

B-type natriuretic peptide at the early stage of univentricular circulation reflects inadequate adaptation to volume overload

B-type natriuretic peptide at the early stage of univentricular circulation reflects inadequate adaptation to volume overload

A clinical importance of natriuretic peptides in pediatric practice

Biomarkers in congenital heart disease: do natriuretic peptides hold the key?

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